DL-2-氨基-1-戊醇合成路线 （共 10 条）
反应条件
2: (i) H2SO4, (ii) (heating) View Scheme
参考文献
Cerbai; Turbanti; Bianchini; Bramanti; Tellini
Bollettino chimico farmaceutico, 1967 , vol. 106, # 12 p. 837 - 854
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Purification / work up;
参考文献
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; ARMSTRONG, Daniel, W.; PING, Sun; BREITBACH, Zachary, S.; WANG, Chunlei
Patent: WO2010/148191 A2, 2010 ;
Location in patent: Page/Page column 45-49; 59 ;
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Purification / work up;
参考文献
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; ARMSTRONG, Daniel, W.; PING, Sun; BREITBACH, Zachary, S.; WANG, Chunlei
Patent: WO2010/148191 A2, 2010 ;
Location in patent: Page/Page column 45-49; 59 ;
反应条件
sodium tetrahydroborate; aluminium trichloride in diethylene glycol dimethyl ether
参考文献
Handrick; Atkinson; Granchelli; Bruni
Journal of medicinal chemistry, 1965 , vol. 8, # 6 p. 762 - 766
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Piper; Stringfellow Jr.; Johnston
Journal of medicinal chemistry, 1966 , vol. 9, # 6 p. 911 - 920
反应条件
1: H2 / Pd/C
2: LiAlH4
3: Na/NH3
View Scheme
参考文献
Ukaji, Yutaka; Kume, Kouji; Watai, Toshiyuki; Fujisawa, Tamotsu
Chemistry Letters, 1991 , # 1 p. 173 - 176
反应条件
tetrahydrofuran; lithium aluminium tetrahydride
参考文献
Pfeil; Barth
Justus Liebigs Annalen der Chemie, 1955 , vol. 593, p. 81,87
Full Text Show Details
Vogl; Poehm
Monatshefte fuer Chemie, 1952 , vol. 83, p. 541
参考文献
Ukaji, Yutaka; Kume, Kouji; Watai, Toshiyuki; Fujisawa, Tamotsu
Chemistry Letters, 1991 , # 1 p. 173 - 176
反应条件
methanol; nickel
Hydrogenation.unter Druck;
参考文献
Purdue Research.Found.
Patent: US2139123 , 1937 ;
反应条件
lithium aluminium tetrahydride
参考文献
Feibush,B. et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1979 , p. 1230 - 1236
