1-甲氧基-2-苯基乙炔-苯合成路线 （共 52 条）
反应条件
sodium methylate; triphenylphosphine; palladium diacetate in methanol T=25°C; 48 h;
参考文献
Tetrahedron Letters, , vol. 44, # 9 p. 1979 - 1981
反应条件
anhydrous iron chloride in dichloromethane T=45°C; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 75, # 16 p. 5701 - 5706
反应条件
N-iodo-succinimide; trimethylsilylazide in 1,2-dichloro-ethane; acetonitrile T=20 - 70°C; 3 h;
参考文献
Organic Letters, , vol. 15, # 11 p. 2571 - 2573
反应条件
toluene-4-sulfonic acid in ethanol T=170°C; microwave irradiation;
参考文献
Jacubert, Maud; Hamze, Abdallah; Provot, Olivier; Peyrat, Jean-Francois; Brion, Jean-Daniel; Alami, Mouad
Tetrahedron Letters, 2009 , vol. 50, # 26 p. 3588 - 3592
反应条件
pyrrolidine
T=85°C; Sonogashira coupling; 1.5 h;
参考文献
Carpita, Adriano; Ribecai, Arianna
Tetrahedron Letters, 2009 , vol. 50, # 2 p. 204 - 207
反应条件
copper(l) iodide; potassium carbonate; triphenylphosphine in water
T=100°C; 24 h; Inert atmosphere;
参考文献
Li, Tingyi; Sun, Peng; Yang, Hailong; Zhu, Yan; Yan, Hong; Lu, Linhua; Mao, Jincheng
Tetrahedron, 2012 , vol. 68, # 32 p. 6413 - 6419
反应条件
piperidine; [Pd(H3CCOCHC(NCH2C6H4OCH3)CH3)(CH3)(P(C6H5)3)]
T=40°C; Sonogashira coupling; 4 h;
参考文献
Lee, Dong-Hwan; Qiu, Huili; Cho, Min-Ho; Lee, Ik-Mo; Jin, Myung-Jong
Synlett, 2008 , # 11 p. 1657 - 1660
反应条件
dichloro bis(acetonitrile) palladium(II); caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in various solvent(s)
T=97°C; Sonogashira coupling; 3 h;
参考文献
Gelman, Dmitri; Buchwald, Stephen L.
Angewandte Chemie - International Edition, 2003 , vol. 42, # 48 p. 5993 - 5996
反应条件
KOC(O)Ph; triphenylphosphine; copper(l) chloride in 1,3-dimethyl-imidazolidin-2-one
T=120°C; Sila-Sonogashira-Hagihara cross-coupling reaction; 12 h; Inert atmosphere;
参考文献
Ihara, Hideki; Ueda, Akinori; Suginome, Michinori
Chemistry Letters, 2011 , vol. 40, # 9 p. 972 - 974
反应条件
ammonia; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; water
T=20°C; P=760 Torr; 24 h;
参考文献
Mohamed Ahmed, Mohamed S.; Sekiguchi, Akitoshi; Masui, Kentaro; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 1 p. 160 - 168
