N-Cbz-DL-丙氨酸合成路线 （共 26 条）
反应条件
sodium carbonate in tetrahydrofuran; water T=0 - 20°C; 2 h;
参考文献
Das, Sajal Kumar; Frey, Joseph
Tetrahedron Letters, 2012 , vol. 53, # 30 p. 3869 - 3872
反应条件
sodium hydride in N,N-dimethyl-formamide T=-5°C; 5 h;
参考文献
Kashima, Choji; Tsuruoka, Shiro; Mizuhara, Saori
Tetrahedron, 1998 , vol. 54, # 49 p. 14679 - 14688
反应条件
indium; ammonium chloride in ethanol Debenzylation; 18 h; Heating;
参考文献
Pitts; Harrison; Moody
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 955 - 977
反应条件
sodium hydroxide; phosphate buffer T=25°C; 170 h; porcine pancreatic lipase, pH=7.0; Yield given;
参考文献
Miyazawa, Toshifumi; Iwanaga, Hitoshi; Ueji, Shinichi; Yamada,Takashi; Kuwata, Shigeru
Chemistry Letters, 1989 , p. 2219 - 2222
反应条件
1: toluene / anfangs unter Kuehlung 2: aqueous NaOH / unter Kuehlung View Scheme
参考文献
Bergmann; Zervas
Chemische Berichte, 1932 , vol. 65, p. 1192,1198
反应条件
diethyl ether; phosphorus tribromide
参考文献
Colonna, Stefano; Molinari, Henriette; Banfi, Stefano; Julia, Sebastian; Masana, Jaume; Alvarez, Angel
Tetrahedron, 1983 , vol. 39, # 9 p. 1635 - 1642
反应条件
(i) carbonyldiimidazole, THF, (ii) HN(SiMe3)2, (iii) (hydrolysis); Multistep reaction;
参考文献
Zehavi,U.; Ben-Ishai,D.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1097 - 1101
反应条件
resolved on CSP cellulose tris(3,5-dimethylphenylcarbamate) by chiral HPLC;
参考文献
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; ARMSTRONG, Daniel, W.; PING, Sun; BREITBACH, Zachary, S.; WANG, Chunlei
Patent: WO2010/148191 A2, 2010 ;
Location in patent: Page/Page column 45-49; 51 ;
反应条件
D,L-Cysteine; papain T=40°C; gepufferte wss. Loesung (pH 5);
参考文献
Polglase; Smith
Journal of the American Chemical Society, 1949 , vol. 71, p. 3083
反应条件
citrate buffer; dl-cysteine hydrochloride; papain T=50°C; 24 h;
参考文献
Moriniere, J. L.; Danree, B.; Lemoine, J.; Guy, A.
Synthetic Communications, 1988 , vol. 18, # 4 p. 441 - 444
