2,3-二氨基-5-溴-4-甲基吡啶合成路线 （共 6 条）
反应条件
1: With hydrogenchloride; tin(ll) chloride in water T=0 - 100°C; 2: With water; sodium hydroxide
参考文献
Wu, Runzhi; Smidansky, Eric D.; Oh, Hyung Suk; Takhampunya, Ratree; Padmanabhan, Radhakrishnan; Cameron, Craig E.; Peterson, Blake R.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7958 - 7966
反应条件
1: concentrated H2SO4; concentrated HNO3 2: SnCl2; aqueous HCl View Scheme
参考文献
Daiichi Sankyo Company, Limited
Patent: US2011/82138 A1, 2011 ;
US 20110082138 A1
反应条件
1: ethanol; bromine 2: concentrated H2SO4; concentrated HNO3 3: SnCl2; aqueous HCl View Scheme
参考文献
Wu, Runzhi; Smidansky, Eric D.; Oh, Hyung Suk; Takhampunya, Ratree; Padmanabhan, Radhakrishnan; Cameron, Craig E.; Peterson, Blake R.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7958 - 7966
反应条件
1 h; Erfllectrochemical reaction;
参考文献
Wu, Runzhi; Smidansky, Eric D.; Oh, Hyung Suk; Takhampunya, Ratree; Padmanabhan, Radhakrishnan; Cameron, Craig E.; Peterson, Blake R.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7958 - 7966
反应条件
1: aqueous HCl; NaNO2 2: palladium/charcoal; platinum; aq. NaOH solution / Hydrogenation View Scheme
参考文献
Graboyes; Day
Journal of the American Chemical Society, 1957 , vol. 79, p. 6421,6423,6424
反应条件
1: 1 h / Erfllectrochemical reaction 2: 10 palladium on activated carbon; platinum(IV) oxide; hydrogen; sodium hydroxide / water / 0.5 h / 2585.81 Torr View Scheme
参考文献
Wu, Runzhi; Smidansky, Eric D.; Oh, Hyung Suk; Takhampunya, Ratree; Padmanabhan, Radhakrishnan; Cameron, Craig E.; Peterson, Blake R.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7958 - 7966
