1-(氨甲酰甲基)吡啶氯合成路线 （共 18 条）
反应条件
in acetone 20 h; Heating;
参考文献
Katritzky, Alan R.; Grzeskowiak, Nicholas E.; Alvarez-Builla, Julio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1180 - 1185
反应条件
pyridine in acetonitrile T=90°C; 10 h;
参考文献
Goehring, Wolfgang; Harrington, Peter John; Hodges, Lewis M.; Johnston, David A.; Rimmler, Goesta
Patent: US2005/14792 A1, 2005 ;
Location in patent: Page/Page column 6 ;
US 20050014792 A1
反应条件
sodium hydroxide; acetic acid 1.) methanol, RT, 15 min, 2.) methanol, RT, 1 h; Yield given. Multistep reaction;
参考文献
Labaudiniere, Richard; Dereu, Norbert; Cavy, Francois; Guillet, Marie-Christine; Marquis, Olivier; Terlain, Bernard
Journal of Medicinal Chemistry, 1992 , vol. 35, # 23 p. 4315 - 4324
反应条件
sodium hydroxide; acetic acid 1.) methanol, RT, 15 min, 2.) methanol, RT, 1 h; Yield given. Multistep reaction;
参考文献
Labaudiniere, Richard; Dereu, Norbert; Cavy, Francois; Guillet, Marie-Christine; Marquis, Olivier; Terlain, Bernard
Journal of Medicinal Chemistry, 1992 , vol. 35, # 23 p. 4315 - 4324
反应条件
sodium hydroxide; acetic acid 1.) methanol, RT, 15 min, 2.) methanol, RT, 1 h; Yield given. Multistep reaction;
参考文献
Labaudiniere, Richard; Dereu, Norbert; Cavy, Francois; Guillet, Marie-Christine; Marquis, Olivier; Terlain, Bernard
Journal of Medicinal Chemistry, 1992 , vol. 35, # 23 p. 4315 - 4324
反应条件
methanol; potassium hydroxide; water
参考文献
Thesing; Mueller
Chemische Berichte, 1957 , vol. 90, p. 711,720
反应条件
1: 2-formyl-3-o-tolyl-acrylonitrile; 1-carbamoylmethylpyridinium chloride With triethylamine in methanol
T=20 - 30°C; 2 h;
2: N-(chloromethylene)-N-methylmethanaminium chloride in dichloromethane
T=45 - 190°C; 1.25 h;
参考文献
Goehring, Wolfgang; Harrington, Peter John; Hodges, Lewis M.; Johnston, David A.; Rimmler, Goesta
Patent: US2005/14792 A1, 2005 ;
Location in patent: Page column 7 ;
US 20050014792 A1
参考文献
Goehring, Wolfgang; Harrington, Peter John; Hodges, Lewis M.; Johnston, David A.; Rimmler, Goesta
Patent: US2005/14792 A1, 2005 ;
Location in patent: Page/Page column 8 ;
US 20050014792 A1
参考文献
Goehring, Wolfgang; Harrington, Peter John; Hodges, Lewis M.; Johnston, David A.; Rimmler, Goesta
Patent: US2005/14792 A1, 2005 ;
Location in patent: Page/Page column 8 ;
US 20050014792 A1
参考文献
Goehring, Wolfgang; Harrington, Peter John; Hodges, Lewis M.; Johnston, David A.; Rimmler, Goesta
Patent: US2005/14792 A1, 2005 ;
Location in patent: Page/Page column 8 ;
US 20050014792 A1
