反应条件
1: dichloromethane / 20 °C 2: sec.-butyllithium; N,N,N',N,-tetramethylethylenediamine / tetrahydrofuran / -78 - 20 °C 3: hydrogenchloride / water / |Reflux 4: potassium carbonate / N,N-dimethyl-formamide / 20 °C View Scheme
参考文献
Fevig, John M.; Feng, Jianxin; Rossi, Karen A.; Miller, Keith J.; Wu, Ginger; Hung, Chen-Pin; Ung, Thao; Malmstrom, Sarah E.; Zhang, Ge; Keim, William J.; Cullen, Mary Jane; Rohrbach, Kenneth W.; Qu, Qinling; Gan, Jinping; Pelleymounter, Mary Ann; Robl, Jeffrey A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 330 - 335
