反-2-氯-3,4-二甲氧基-β-硝基苯乙烯合成路线 （共 2 条）
反应条件
1: With AlCl3, aluminium chloride; lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 16.66 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; water Inert atmosphere;
参考文献
GLAXO GROUP LIMITED; SHIONOGI and CO., LTD.; LIAO, Xiangmin; PEARSON, Neil, David; PENDRAK, Israil; SANO, Masayuki
Patent: WO2013/52568 A1, 2013 ;
Location in patent: Page/Page column 74; 75 ;
反应条件
1: 80 percent / LiAlH4, AlCl3 / tetrahydrofuran / 16 h / Ambient temperature 2: Me3SiI / CHCl3; tetrahydrothiophene 1,1-dioxide / 72 h / 50 °C View Scheme
参考文献
McCarthy, James R.; McCowan, Jefferson; Zimmerman, Mark B.; Wenger, Marcia A.; Emmert, Lee W.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1586 - 1590
