2,5-脱水-D-甘露醇合成路线 （共 31 条）
反应条件
sulfuric acid in water T=125 - 145°C; P=18 - 20 Torr; Industry scale;
参考文献
E. I. DU PONT DE NEMOURS AND COMPANY
Patent: WO2003/89436 A1, 2003 ;
Location in patent: Page/Page column 21-23 ;
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; Hydrogenolysis; 18 h;
参考文献
Persky, Rachel; Albeck, Amnon
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5632 - 5638
反应条件
sodium tetrahydroborate in water 24 h;
参考文献
Bendiak, Brad; Salayan, Mary E.; Pantoja, Mario
Journal of Organic Chemistry, 1995 , vol. 60, # 25 p. 8245 - 8256
反应条件
sodium methylate in methanol T=20°C;
参考文献
Cassel, Stephanie; Debaig, Catherine; Benvegnu, Thierry; Chaimbault, Patrick; Lafosse, Michel; Plusquellec, Daniel; Rollin, Patrick
European Journal of Organic Chemistry, 2001 , # 5 p. 875 - 896
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Van Delft, Floris L.; Valentijn, A. Rob P.M.; Van Der Marel, Gijs A.; Van Boom, Jacques H.
Journal of Carbohydrate Chemistry, 1999 , vol. 18, # 2 p. 165 - 190
反应条件
zinc(II) chloride in water
参考文献
BIOeCON International Holding N.V.; Van Den Bergh, Johan; Moulijn, Jacob Adriaan
Patent: EP2615093 A1, 2013 ;
Location in patent: Paragraph 0092; 0093; 0094 ;
反应条件
Amberlite IR-120 (H+) T=170°C; P=10 Torr; 2 h;
参考文献
Bock, Klaus; Pedersen, Christian; Thoegersen, Henning
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1981 , vol. 35, # 6 p. 441 - 450
反应条件
1: 80 percent / NaBH4 / ethanol / 2 h 2: 100 percent / H2 / Pd/C / methanol / 18 h / 20 °C View Scheme
参考文献
Persky, Rachel; Albeck, Amnon
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5632 - 5638
反应条件
1.1: 4-methylmorpholine N-oxide; OsO4 / tetrahydrofuran; H2O / 20 °C 1.2: 50 percent / NaIO4 / methanol; tetrahydrofuran; H2O / 2 h / 20 °C 2.1: Et3N / dimethylformamide; H2O / 18 h / 20 °C 3.1: 80 percent / NaBH4 / ethanol / 2 h 4.1: 100 percent / H2 / Pd/C / methanol / 18 h / 20 °C View Scheme
参考文献
Persky, Rachel; Albeck, Amnon
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5632 - 5638
反应条件
1.1: 4-methylmorpholine N-oxide; OsO4 / tetrahydrofuran; H2O / 20 °C 1.2: 76 percent / NaIO4 / methanol; tetrahydrofuran; H2O / 2 h / 20 °C 2.1: 80 percent / NaBH4 / ethanol / 2 h 3.1: 100 percent / H2 / Pd/C / methanol / 18 h / 20 °C View Scheme
参考文献
Persky, Rachel; Albeck, Amnon
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5632 - 5638
