N-Boc-L-高丝氨酸合成路线 （共 10 条）
反应条件
sodium hydroxide in tetrahydrofuran; ethanol; water T=23°C; 16 h;
参考文献
Ozinskas; Rosenthal
Journal of Organic Chemistry, 1986 , vol. 51, # 26 p. 5047 - 5050
反应条件
hydrogen; palladium on activated charcoal in methanol 20 h; Ambient temperature;
参考文献
Sajiki, Hironao
Tetrahedron Letters, 1995 , vol. 36, # 20 p. 3465 - 3468
反应条件
sodium chloride; sodium hydrogencarbonate in 1,4-dioxane; N-methyl-acetamide; ethyl acetate
参考文献
Meiji Seika Kaisha, Ltd.
Patent: US5334723 A1, 1994 ;
反应条件
potassium hydroxide T=20°C; 12 h;
参考文献
Sanchez, Adrian; Calderon, Ernesto; Vazquez, Alfredo
Synthesis (Germany), 2013 , vol. 45, # 10 art. no. SS-2012-M0583-OP, p. 1364 - 1372
反应条件
ammonia; sodium dry-ice-cooled; Yield given;
参考文献
Schoen, Istvan; Szirtes, Tamas; Ueberhardt, Tamas
Journal of the Chemical Society, Chemical Communications, 1982 , # 11 p. 639 - 640
反应条件
1: triethylamine / dichloromethane / 17 h / 20 °C / |Inert atmosphere 2: potassium hydroxide / 12 h / 20 °C View Scheme
参考文献
Sanchez, Adrian; Calderon, Ernesto; Vazquez, Alfredo
Synthesis (Germany), 2013 , vol. 45, # 10 art. no. SS-2012-M0583-OP, p. 1364 - 1372
反应条件
magnesium oxide in 1,4-dioxane; water
参考文献
Buku,A. et al.
Justus Liebigs Annalen der Chemie, 1976 , p. 417 - 431
反应条件
(i) Na, liq. NH3, (ii) /BRN= 385801/; Multistep reaction;
参考文献
Buku,A. et al.
Justus Liebigs Annalen der Chemie, 1976 , p. 417 - 431
反应条件
4-(N,N-dimethlyamino)pyridine; benzotriazol-1-ol; dicyclohexyl-carbodiimide in tetrahydrofuran T=23°C; 16 h;
参考文献
Stachel; Chul Bom Lee; Spassova; Chappell; Bornmann; Danishefsky; Chou; Guan
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4369 - 4378
反应条件
in diethyl ether; ethyl acetate T=50°C;
参考文献
Journal of Peptide Science, , vol. 19, # 5 p. 308 - 314
