2-氯甲基-1,3-苯并恶唑合成路线 (共 18 条)
反应条件
in dichloromethane T=0 - 20°C;
参考文献
Sheng, Chunquan; Che, Xiaoying; Wang, Wenya; Wang, Shengzheng; Cao, Yongbing; Yao, Jianzhong; Miao, Zhenyuan; Zhang, Wannian
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 5 p. 1706 - 1712
反应条件
triethylamine in ethyl acetate Ambient temperature;
参考文献
Olagbemiro; Agho; Abayeh; Amupitan
Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands, 1996 , vol. 115, # 6 p. 337 - 338
反应条件
boron trifluoride diethyl etherate in dichloromethane T=20°C; Inert atmosphere;
参考文献
Bastug, Gulluzar; Eviolitte, Christophe; Marko, Istvan E.
Organic Letters, 2012 , vol. 14, # 13 p. 3502 - 3505
反应条件
phosphoric acid triethylester in 1,2-dichloro-ethane 2 h; Heating;
参考文献
Kosaka, Takatoshi; Wakabayashi, Toshio
Heterocycles, 1995 , vol. 41, # 3 p. 477 - 486
反应条件
1.1: 59 percent / ethyl acetate / 0.43 h / 20 °C 2.1: PPA / 0.5 h / 150 °C 2.2: 57 percent / aq. NH3 View Scheme
参考文献
Burkholder, Conrad R.; Dolbier Jr., William R.; Medebielle, Maurice
Journal of Fluorine Chemistry, 2000 , vol. 102, # 1-2 p. 369 - 376
反应条件
in dichloromethane Ambient temperature;
参考文献
Musser; Kubrak; Chang; DiZio; Hite; Hand; Lewis
Journal of medicinal chemistry, 1987 , vol. 30, # 2 p. 400 - 405
参考文献
Ribeiro Morais, Goreti; Vicente Miranda, Hugo; Santos, Isabel C.; Santos, Isabel; Outeiro, Tiago F.; Paulo, Antonio
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 24 p. 7698 - 7710
反应条件
in ethyl acetate Ambient temperatureother ketenes;
参考文献
Olagbemiro; Agho; Abayeh; Amupitan
Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands, 1996 , vol. 115, # 6 p. 337 - 338
反应条件
Na2CS3 in water T=20°C; 1.5 h;
参考文献
Kalai, Tamas; Jeko, Jozsef; Osz, Erzsebet; Hideg, Kalman
Synthetic Communications, 2003 , vol. 33, # 9 p. 1433 - 1442
参考文献
Kosaka, Takatoshi; Wakabayashi, Toshio
Heterocycles, 1995 , vol. 41, # 3 p. 477 - 486