N-甲基-2,2-二氨基二乙胺合成路线 （共 7 条）
反应条件
potassium carbonate in ethanol T=80°C; 96 h; Heating;
参考文献
Garrigues, Bernard; Vidaud, Lionel
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 10 p. 775 - 786
反应条件
ammonia; sodium carbonate in water-d2 Title compound not separated from byproducts;
参考文献
Golding, Bernard T.; Kebbell, Michael J.; Lockhart, Ian M.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1987 , p. 705 - 714
参考文献
Schwarzenbach et al.
Helvetica Chimica Acta, 1957 , vol. 40, p. 1886,1896
反应条件
hydrogenchloride; water 1.) 100 deg C, 4 h; 2.) 90 deg C, 50 h; Yield given. Multistep reaction;
参考文献
Riggio; Hopff; Hofmann; Waser
Helvetica Chimica Acta, 1980 , vol. 63, # 2 p. 488 - 497
反应条件
(i) phthalimide <K salt>, (ii) aq. HCl; Multistep reaction;
参考文献
Sieber,G.
Journal fuer Praktische Chemie (Leipzig), 1970 , vol. 312, p. 507 - 518
反应条件
4-(N,N-dimethlyamino)pyridine in chloroform T=20°C; 16 h;
参考文献
Palus; Chojnacka; Piasecki; Zboinska; Mlochowski
Polish Journal of Chemistry, 2004 , vol. 78, # 11-12 p. 2117 - 2126
反应条件
in dichloromethane T=0°C; 0.75 h;
参考文献
CATABASIS PHARMACEUTICALS, INC.; MILNE, Jill, C.; JIROUSEK, Michael, R.; BEMIS, Jean, E.; VU, Chi, B.; TING, Amal
Patent: WO2012/115695 A1, 2012 ;
Location in patent: Page/Page column 78-79 ;
