6-甲氧基-2(3H)-苯并噻唑酮合成路线 （共 6 条）
反应条件
1: With copper(l) iodide; Na2S*9H2O in N,N-dimethyl-formamide T=80°C; Inert atmosphere; 2: With acetic acid in N,N-dimethyl-formamide T=130°C; 36 h; Inert atmosphere;
参考文献
Li, Jiaojiao; Zhang, Yihua; Jiang, Yongwen; Ma, Dawei
Tetrahedron Letters, 2012 , vol. 53, # 20 p. 2511 - 2513
参考文献
Boehringer Ingelheim GmbH
Patent: US4328235 A1, 1982 ;
反应条件
hydrogenchloride; formic acid; acetic acid; sodium nitrite 1.) -10 deg C, 2.) reflux, 24 h;
参考文献
Jones; Venuti; Alvarez; Bruno; Berks; Prince
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303
反应条件
sodium hydroxide; potassium permanganate anschliessend Behandeln mit wss. HCl;
参考文献
I.G. Farbenind.
Patent: US2108712 , 1934 ;
Full Text Show Details
I.G. Farbenind.
Patent: DE615131 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 22, p. 324
反应条件
hydrogen bromide
1 h; Heating;
参考文献
Jones; Venuti; Alvarez; Bruno; Berks; Prince
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303
反应条件
1: 76 percent / 0.2 N aq. NaOH / 4 h / 20 °C
2: 88 percent / BBr3 / CH2Cl2 / 5 h / 20 °C
View Scheme
参考文献
Delhomel; Yous; Depreux; Lesieur
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 3 p. 633 - 639
