2-羟基-1-(4-甲基苯基)乙酮合成路线 （共 37 条）
反应条件
1: 97 percent / CH2Cl2 / 1 h / 0 °C
2: 83 percent / Et3N / CH2Cl2; methanol / 12 h / 20 °C
View Scheme
参考文献
Craig, Donald; Daniels, Kevin; MacKenzie, A. Roderick
Tetrahedron, 1993 , vol. 49, # 48 p. 11263 - 11304
反应条件
poly[4-(diacetoxyiodo)styrene]; sodium hydroxide
T=0°C; Oxidation;
参考文献
Togo, Hideo; Abe, Seiichiro; Nogami, Genki; Yokohama, Masataka
Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 10 p. 2351 - 2356
反应条件
in methanol
T=25°C; Kinetics; Concentration;
参考文献
Tagawa, Kohei; Sasagawa, Keita; Wakisaka, Ken; Monjiyama, Shunsuke; Katayama, Mika; Yamataka, Hiroshi
Bulletin of the Chemical Society of Japan, 2014 , vol. 87, # 1 p. 119 - 126
反应条件
in methanol
T=25°C; Kinetics; Concentration;
参考文献
Tagawa, Kohei; Sasagawa, Keita; Wakisaka, Ken; Monjiyama, Shunsuke; Katayama, Mika; Yamataka, Hiroshi
Bulletin of the Chemical Society of Japan, 2014 , vol. 87, # 1 p. 119 - 126
反应条件
in acetone
T=25°C; 3 h;
参考文献
Kovac, F.; Baumstark, A. L.
Tetrahedron Letters, 1994 , vol. 35, # 47 p. 8751 - 8754
反应条件
1: CH2Cl2 / 17 h / Ambient temperature
2: silica gel / CH2Cl2; methanol
View Scheme
参考文献
Boyer, Joseph H.; Natesh, Anbazhagan
Synthesis, 1988 , # 12 p. 980 - 981
反应条件
in tetrahydrofuran
T=-78 - 25°C; 0.5 h;
参考文献
Katritzky, Alan R.; Sengupta, Saumitra
Tetrahedron Letters, 1987 , vol. 28, # 17 p. 1847 - 1850
反应条件
1.1: isopropylmagnesium chloride / tetrahydrofuran / 1.17 h / 20 - 30 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
1.3: 30 °C / Inert atmosphere
2.1: hydrogenchloride; water / methanol / 40 °C / Inert atmosphere
View Scheme
参考文献
McLaughlin, Mark; Belyk, Kevin M.; Qian, Gang; Reamer, Robert A.; Chen, Cheng-Yi
Journal of Organic Chemistry, 2012 , vol. 77, # 11 p. 5144 - 5148
反应条件
toluene-4-sulfonic acid in tetrahydrofuran; water
4.5 h; Reflux;
参考文献
Liu, Hui; Dong, Chao; Zhang, Zeguang; Wu, Peiyu; Jiang, Xuefeng
Angewandte Chemie - International Edition, 2012 , vol. 51, # 50 p. 12570 - 12574
Angew. Chem., 2012 , vol. 124, # 50 p. 12738 - 12742,5
反应条件
tris(trifluoroacetoxy)-λ3-iodane in chloroform
6 h; Ambient temperaturefurther solvent and reaction time; Product distribution;
参考文献
Fukuyama, Norihiro; Nishino, Hiroshi; Kurosawa, Kazu
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 12 p. 4363 - 4368
