2-羟基-1-(4-甲基苯基)乙酮合成路线 （共 37 条）
反应条件
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide T=80°C; 2 h;
参考文献
Zhu, Yan-Ping; Jia, Feng-Cheng; Liu, Mei-Cai; Wu, An-Xin
Organic Letters, 2012 , vol. 14, # 17 p. 4414 - 4417
反应条件
pyridine; formic acid; chlorosulphonyl isocyanate in acetonitrile T=0 - 10°C; Inert atmosphere;
参考文献
Wang, You-Qing; Yu, Chang-Bin; Wang, Da-Wei; Wang, Xiao-Bing; Zhou, Yong-Gui
Organic Letters, 2008 , vol. 10, # 10 p. 2071 - 2074
反应条件
in methanol T=20 - 30°C; Mechanism;
参考文献
Morozov, A. A.
Russian Journal of Physical Chemistry, 1984 , vol. 58, # 12 p. 1823 - 1826
Zhurnal Fizicheskoi Khimii, 1984 , vol. 58, p. 3006 - 3009
反应条件
1: triethylamine / dichloromethane / 20 °C / Inert atmosphere 2: Ni(PCy3)2Cl2; sodium t-butanolate / N,N-dimethyl-formamide; toluene / 0.67 h / 100 °C / Inert atmosphere View Scheme
参考文献
Chemical Communications, , vol. 47, # 25 p. 7224 - 7226
反应条件
sodium hydroxide in methanol; water T=20 - 30°C; var. solv.: DMF, DMSO and water; Mechanism;
参考文献
Morozov, A. A.
Russian Journal of Physical Chemistry, 1984 , vol. 58, # 12 p. 1823 - 1826
Zhurnal Fizicheskoi Khimii, 1984 , vol. 58, p. 3006 - 3009
反应条件
lithium hydroxide Multistep reaction;
参考文献
Morozov, A. A.
J. Gen. Chem. USSR (Engl. Transl.), 1989 , vol. 59, # 1.2 p. 215 - 222,186 - 192
反应条件
β-cyclodextrin; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in water; acetone
T=20°C; 12 h;
参考文献
Krishnaveni, N. Srilakshmi; Surendra; Rao, K. Rama
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 2-3 p. 346 - 350
反应条件
1: With β-cyclodextrin in water; acetone
T=20 - 60°C;
2: With N-bromosuccinmide in water; acetone
T=20°C; 24 h;
参考文献
Surendra; Krishnaveni, N. Srilakshmi; Reddy, M. Arjun; Nageswar; Rao, K. Rama
Journal of Organic Chemistry, 2003 , vol. 68, # 23 p. 9119 - 9121
反应条件
hydrogenchloride; water in methanol
T=40°C; Inert atmosphere;
参考文献
McLaughlin, Mark; Belyk, Kevin M.; Qian, Gang; Reamer, Robert A.; Chen, Cheng-Yi
Journal of Organic Chemistry, 2012 , vol. 77, # 11 p. 5144 - 5148
反应条件
potassium phosphate buffer; thiamine diphosphate; magnesium sulfate; benzaldehyde lyase from Pseudomonas fluorescens in dimethyl sulfoxide
T=37°C; pH=7.0; Enzymatic reaction;
参考文献
Demir, Ayhan S.; Ayhan, Peruze; Igdir, A. Cigdem; Duygu, A. Nese
Tetrahedron, 2004 , vol. 60, # 31 p. 6509 - 6512
