3-(4-异丁基-苯基)-丙醛合成路线 （共 8 条）
反应条件
hydrogen; [rhodium(I)(carbonyl)2(acetylacetonate)]; (R,S)-Ph2P-binaphthyl-cyclic binaphthylphosphoramidite in benzene
T=60°C; P=15200 Torr; 24 h;
参考文献
Yan, Yongjun; Zhang, Xumu
Journal of the American Chemical Society, 2006 , vol. 128, # 22 p. 7198 - 7202
反应条件
[rhodium(I)(carbonyl)2(acetylacetonate)]; hydrogen; (R,S)-Binaphos in benzene
T=60°C; P=38000 Torr; 66 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Nozaki, Kyoko; Sakai, Nozomu; Nanno, Tetsuo; Higashijima, Takanori; Mano, Satoshi; Horiuchi, Toshihide; Takaya, Hidemasa
Journal of the American Chemical Society, 1997 , vol. 119, # 19 p. 4413 - 4423
反应条件
1: 78 percent / potassium bisulfate, p-methoxyphenol / 200 °C
2: H2, SnCl2*2H2O, p-methoxyphenol / <(-)BPPM>PtCl2 / benzene / 9 h / 60 °C / 124116 Torr
View Scheme
参考文献
Parrinello, Giovanni; Stille, J. K.
Journal of the American Chemical Society, 1987 , vol. 109, # 23 p. 7122 - 7127
反应条件
tetracarbonylbis(μ-chloro)dirhodium(I); hydrogen; 1,2,5-triphenyl-1H-phosphole; triethylamine in toluene
T=25°C; P=15001.2 Torr; 6 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Neibecker, Denis; Reau, Regis; Lecolier, Serge
Journal of Organic Chemistry, 1989 , vol. 54, # 22 p. 5208 - 5210
反应条件
1: 54 percent / potassium hydroxide, 3-tert-butyl catechol, tetrabutylammonium bromide / 1 h / 120 °C
2: H2, <Rh(CO)2Cl>2, 1,2,5-triphenylphosphole, triethylamine / toluene / 6 h / 25 °C / 15001.2 Torr
View Scheme
参考文献
Neibecker, Denis; Reau, Regis; Lecolier, Serge
Journal of Organic Chemistry, 1989 , vol. 54, # 22 p. 5208 - 5210
参考文献
INTERNATIONAL FLAVORS and FRAGRANCES INC.
Patent: EP2333038 B1, 2012 ;
参考文献
Levorse, JR., Anthony T.; Belko, Robert P.; Amorelli, Benjamin; Narula, Anubhav P.S.; Monteleone, Michael G.
Patent: US2011/118170 A1, 2011 ;
反应条件
cis-PtCl(SnCl3)(SS-BDPP); hydrogen in toluene
T=20°C; P=52504.2 Torr; 336 h; reactions under var. conditions with var. catalysts; Product distribution;
参考文献
Toth, Imre; Elsevier, Cornelis J.; De Vries, Johannes G.; Bakos, Jozsef; Smeets, Wilberth J. J.; Spek, Anthony L.
Journal of Organometallic Chemistry, 1997 , vol. 540, # 1-2 p. 15 - 25
