4-苄氧基-2-溴-5-甲氧基-苯甲醛合成路线 （共 18 条）
反应条件
1: NaBH4 / tetrahydrofuran / 4 h / 0 °C 2: CBr4; triphenylphosphine / methanol / 20 °C View Scheme
参考文献
Fukuyama, Yoshiyasu; Yaso, Hideyuki; Mori, Takashi; Takahashi, Hironobu; Minami, Hiroyuki; Kodama, Mitsuaki
Heterocycles, 2001 , vol. 54, # 1 p. 259 - 274
反应条件
potassium phosphate; copper(l) iodide; 1,10-phenanthroline in 1,4-dioxane
T=80°C; Schlenk technique; SolventTime;
参考文献
Reddy, Alavala Gopi Krishna; Mahendar, Lodi; Satyanarayana, Gedu
Synthetic Communications, 2014 , vol. 44, # 14 p. 2076 - 2087
反应条件
bromine; sodium acetate in acetic acid
T=40°C; 11 h;
参考文献
Fukuyama, Yoshiyasu; Yaso, Hideyuki; Mori, Takashi; Takahashi, Hironobu; Minami, Hiroyuki; Kodama, Mitsuaki
Heterocycles, 2001 , vol. 54, # 1 p. 259 - 274
反应条件
potassium carbonate in ethanol
Alkylation; 18 h; Heating;
参考文献
Gies, Anne-Elisabeth; Pfeffer, Michel
Journal of Organic Chemistry, 1999 , vol. 64, # 10 p. 3650 - 3654
反应条件
sodium hydroxide
T=85°C; 1 h;
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
1: 72 percent / methanol; dimethylsulfoxide; dimethylformamide / 2 h / 150 °C
2: 90 percent / K2CO3 / dimethylformamide / 2 h / 100 °C
3: FeSO4*7H2O, 25 percent NH4OH / 0.08 h / 100 °C
4: 20 percent HBr; NaNO2; 47 percent HBr / CuBr
View Scheme
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
1: 25 percent / phenylmethanol; dimethylsulfoxide / 0.15 h / 150 °C
2: 77 percent / 2 percent NaOH / 1 h / 85 °C
View Scheme
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
pyridinium hydrobromide perbromide in methanol
1.) 0 deg C, 1 h, 2.) r.t., 1 h;
参考文献
Wunsch; Nerdinger
Archiv der Pharmazie, 1995 , vol. 328, # 4 p. 301 - 305
反应条件
1: 90 percent / K2CO3 / dimethylformamide / 2 h / 100 °C
2: FeSO4*7H2O, 25 percent NH4OH / 0.08 h / 100 °C
3: 20 percent HBr; NaNO2; 47 percent HBr / CuBr
View Scheme
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
1: 62 percent / Br2, NaOAc, I2, AcOH / 1.) 45 deg C, 2 h, 2.) room temperature, 16 h
2: 88 percent / KOH / tetrahydrofuran; H2O / 2 h / Ambient temperature
3: 98 percent / dimethylformamide / 3 h / 80 °C
View Scheme
参考文献
Martin
Helvetica Chimica Acta, 1989 , vol. 72, # 7 p. 1554 - 1582
