反应条件
1: 90 percent / (S,S)-cyclo(phenylalanylhistidyl) / toluene / 36 h / -15 °C 2: 97 percent / imidazole / dimethylformamide / 1 h / Ambient temperature 3: 1.) DIBAL; NH4Br, 3.) NaBH4 / 1.) toluene, ether, -70 deg C, 3 h; MeOH, -60 to -70 deg C, 10 min, 2.) toluene, MeOH, -70 deg C to room temp., 40 min, 3.) toluene, MeOH, 0 deg C to room temp., overnight 4: 96 percent / LiAlH4 / tetrahydrofuran / 1 h / Heating 5: 88 percent / Pd(PPh3)2Cl2, Bu3SnH, AcOH / CH2Cl2 / Ambient temperature View Scheme
参考文献
Brown, Roger F. C.; Jackson, W. Roy; McCarthy, Tom D.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 10 p. 2149 - 2150
