N-(4,5-二甲基咪唑-2-基)乙酰胺合成路线 （共 4 条）
反应条件
methanol; sulfuric acid; water 16 h; Heating / reflux;
参考文献
EXELIXIS, INC.
Patent: WO2008/42282 A2, 2008 ;
Location in patent: Page/Page column 193-194 ;
WO 2008/042282 A2
反应条件
in N,N-dimethyl-formamide
96 h; Ambient temperature;
参考文献
Little, Thomas L.; Webber, Stephen E.
Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7299 - 7305
反应条件
in N,N-dimethyl-formamide
96 h; Ambient temperature;
参考文献
Little, Thomas L.; Webber, Stephen E.
Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7299 - 7305
参考文献
Burtles; Pyman
Journal of the Chemical Society, 1925 , vol. 127, p. 2016
