4-甲基-2-吡咯甲酸乙酯合成路线 （共 11 条）
反应条件
palladium on activated charcoal in ethanol P=2585.7 Torr; 16 h;
参考文献
Garrido, Daniel O. A.; Buldain, Graciela; Ojea, Maria I.; Frydman, Benjamin
Journal of Organic Chemistry, 1988 , vol. 53, # 2 p. 403 - 407
反应条件
dodecacarbonyltriiron; trifluoroacetic acid in 1,2-dichloro-ethane T=80°C; 20 h;
参考文献
Nakanishi, Saburo; Otsuji, Yoshio; Itoh, Keiji; Hayashi, Nobuaki
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 12 p. 3595 - 3600
反应条件
1: 80 percent / AlCl3 / CH2Cl2; nitromethane / 18 h / -20 °C 2: 90 percent / 10percent Pd/C / ethanol / 16 h / 2585.7 Torr View Scheme
参考文献
Garrido, Daniel O. A.; Buldain, Graciela; Ojea, Maria I.; Frydman, Benjamin
Journal of Organic Chemistry, 1988 , vol. 53, # 2 p. 403 - 407
反应条件
1: 63 percent / Na2CO3 / 1,2-dichloro-ethane / 3 h / 80 °C 2: 18 percent / Fe3(CO)12, trifluoroacetic acid / 1,2-dichloro-ethane / 20 h / 80 °C View Scheme
参考文献
Nakanishi, Saburo; Otsuji, Yoshio; Itoh, Keiji; Hayashi, Nobuaki
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 12 p. 3595 - 3600
反应条件
triethylamine in acetonitrile RefluxInert atmosphere;
参考文献
Wright, Mathew T.; Carroll, David G.; Smith, Timothy M.; Smith, Stanton Q.
Tetrahedron Letters, 2010 , vol. 51, # 31 p. 4150 - 4152
反应条件
pyridine; 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate 1) r.t. 2) THF, reflux; Yield given. Multistep reaction;
参考文献
Lash, Timothy D.; Hoehner, Michael C.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1671 - 1676
反应条件
quinoline; copper oxide chromium oxide
参考文献
Kondo; Ohno; Sato
Yakugaku Zasshi, 1937 , vol. 57, p. 3; dtsch. Ref. S. 1, 3
Chem.Abstr., 1937 , p. 7055
反应条件
1: 68 percent / POCl3 / Heating 2: 68 percent / aq. KOH / ethanol / Heating View Scheme
参考文献
Sun; Cui, Jean; Liang, Congxin; Zhou, Yong; Nematalla, Asaad; Wang, Xueyan; Chen, Hui; Tang, Cho; Wei, James
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 16 p. 2153 - 2157
反应条件
1: 68 percent / POCl3 / Heating 2: 68 percent / aq. KOH / ethanol / Heating 3: EDC; HOBt; Et3N / dimethylformamide / 20 °C View Scheme
参考文献
Sun; Cui, Jean; Liang, Congxin; Zhou, Yong; Nematalla, Asaad; Wang, Xueyan; Chen, Hui; Tang, Cho; Wei, James
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 16 p. 2153 - 2157
反应条件
potassium hydroxide in ethylene glycol T=200°C;
参考文献
Garrido, Daniel O. A.; Buldain, Graciela; Ojea, Maria I.; Frydman, Benjamin
Journal of Organic Chemistry, 1988 , vol. 53, # 2 p. 403 - 407
