5-甲基-1H-吡咯-3-羧酸甲酯合成路线 （共 10 条）
反应条件
sodium hydride in diethyl ether; dimethyl sulfoxide; mineral oil
T=20°C; 2 h;
参考文献
MENEAR, Keith Allan; Javaid, Muhammad Hashim; Gomez, Sylvie; Hummersone, Marc Geoffrey; Lence, Carlos Fenandez; Martin, Niall Morrison Barr; Rudge, David Alan; Roberts, Craig Anthony; Blades, Kevin
Patent: US2009/192156 A1, 2009 ;
Location in patent: Page/Page column 43-44 ;
反应条件
silver fluoride in acetonitrile
12 h; Ambient temperature;
参考文献
Padwa,A.; Gasdaska,J.R.; Tomas,M.
Journal of the American Chemical Society, 1986 , vol. 108, p. 6739
反应条件
sulfuric acid
144 h; Heating;
参考文献
Padwa,A.; Gasdaska,J.R.; Tomas,M.
Journal of the American Chemical Society, 1986 , vol. 108, p. 6739
反应条件
potassium tert-butylate in tetrahydrofuran
-78 deg C -> r.t; reflux;
参考文献
Katritzky, Alan R.; Cheng, Dai; Musgrave, Richard P.
Heterocycles, 1997 , vol. 44, # 1 p. 67 - 70
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone
1.) irradiation, 2 h, 0 deg C; 2.) benzene, 12 h, r.t.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Padwa,A.; Gasdaska,J.R.; Tomas,M.
Journal of the American Chemical Society, 1986 , vol. 108, p. 6739
反应条件
T=0°C; 2 h; Irradiation; Yield given. Yields of byproduct given;
参考文献
Padwa,A.; Gasdaska,J.R.; Tomas,M.
Journal of the American Chemical Society, 1986 , vol. 108, p. 6739
反应条件
in acetonitrile
T=24.9°C; quenching behavior by the addition of a series of dipolarophiles; var. cond.; Rate constantProduct distributionMechanism;
参考文献
Padwa,A.; Gasdaska,J.R.; Tomas,M.
Journal of the American Chemical Society, 1986 , vol. 108, p. 6739
反应条件
in acetonitrile
T=24.9°C; quenching behavior by the addition of a series of dipolarophiles; var. cond.; Rate constantProduct distributionMechanism;
参考文献
Padwa,A.; Gasdaska,J.R.; Tomas,M.
Journal of the American Chemical Society, 1986 , vol. 108, p. 6739
反应条件
silver fluoride in acetonitrile
T=25°C;
参考文献
Turro, Nicholas J.; Cha, Yuan; Gould, Ian R.; Padwa, Albert; Gasdaska, John R.; Tomas, Miguel
Journal of Organic Chemistry, 1985 , vol. 50, # 22 p. 4415 - 4417
反应条件
methanol; diethyl ether
参考文献
Nicolaus; Mangoni
Annali di Chimica (Rome, Italy), 1956 , vol. 46, p. 847,854
