1-氯-2,3,5-三-O-苄基-D-阿拉伯呋喃糖合成路线 (共 12 条)
反应条件
sodium borohydride in methanol; dichloromethane; water; isopropyl alcohol; acetonitrile
参考文献
Berlex Biosciences Inc.
Patent: US5180824 A1, 1993 ;
反应条件
sodium borohydride in methanol; dichloromethane; water; isopropyl alcohol; acetonitrile
参考文献
Berlex Biosciences Inc.
Patent: US5180824 A1, 1993 ;
反应条件
sodium borohydride in methanol; dichloromethane; water; isopropyl alcohol; acetonitrile
反应条件
1: 3.5 g / triethylamine / acetonitrile / 1.25 h 2: 1.8 g / phosphoryl chloride, triethylamine / CHCl3 / 2 h / Heating 3: 0.2 g / boron trichloride / CH2Cl2 / 2 h / Ambient temperature 4: 68 percent / ammonia / ethanol / 6 h / 150 °C View Scheme
参考文献
Kadir, Kamaliah; Mackenzie, Grahame; Shaw, Gordon
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2304 - 2309
反应条件
sodium borohydride in methanol; dichloromethane; water; isopropyl alcohol; acetonitrile
反应条件
1: 1) sodium hydride (60percent in oil) / 1) acetonitrile, RT, 30 min; 2) acetonitrile, RT, 15 h 2: 62 percent / boron trichloride / CH2Cl2 / 1) -78 deg C, 4 h; 2) from -20 deg C to -30 deg C, 2 h 3: 74 percent / sodium hydrosulfide hydrate / ethanol / 6 h / Heating View Scheme
参考文献
Hanna; Ramasamy; Robins; Revankar
Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1899 - 1903
反应条件
hydrogenchloride in dichloromethane
T=0°C; 2 h;
参考文献
Bartlett; Cook; Holman; McComas; Nowoswait; Poonian; Baird-Lambert; Baldo; Marwood
Journal of Medicinal Chemistry, 1981 , vol. 24, # 8 p. 947 - 954
反应条件
hydrogenchloride in 1,2-dichloro-ethane
T=20°C; Chlorination; 0.166667 h;
参考文献
Subramaniam, Vinodhkumar; Lowary, Todd L.
Tetrahedron, 1999 , vol. 55, # 19 p. 5965 - 5976
反应条件
hydrogenchloride in dichloromethane
T=0°C; 0.166667 h;
参考文献
Kadir, Kamaliah; Mackenzie, Grahame; Shaw, Gordon
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2304 - 2309
反应条件
thionyl chloride in chloroform
5 h; Heating; Yield given;
参考文献
Granata, Alessandro; Perlin, Arthur S.
Carbohydrate Research, 1980 , vol. 86, p. 305 - 308