3-羟基-4-苄氧基苯甲醛合成路线 （共 27 条）
反应条件
sodium hydrogencarbonate; sodium iodide in N,N-dimethyl-formamide T=40°C; 24 h;
参考文献
Plourde, Guy L.; Spaetzel, Randy R.
Molecules, 2002 , vol. 7, # 9 p. 697 - 705
反应条件
potassium carbonate; potassium iodide in acetone Heating;
参考文献
Pez, Didier; Leal, Isabel; Zuccotto, Fabio; Boussard, Cyrille; Brun, Reto; Croft, Simon L.; Yardley, Vanessa; Ruiz Perez, Luis M.; Gonzalez Pacanowska, Dolores; Gilbert, Ian H.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 22 p. 4693 - 4711
反应条件
1: 3,4-dihydroxy-benzaldehyde With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 0.5 h; Inert atmosphere; 2: benzyl chloride in N,N-dimethyl-formamide; mineral oil T=0°C; 12 h;
参考文献
NEUPROTECT PTY LTD; MCLACHLAN, Grant Andrew
Patent: WO2014/56038 A1, 2014 ;
Location in patent: Paragraph 123-125 ;
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran T=0 - 20°C; Mitsunobu reaction; regioselective reaction;
参考文献
Wang, Xiaolong; Ju, Tingting; Li, Xiaodong; Cao, Xiaoping
Synlett, 2010 , # 19 p. 2947 - 2949
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20 - 60°C; 16 h;
参考文献
Van Eis, Maurice J.; Seiler, Paul; Muslinkina, Liya A.; Badertscher, Martin; Pretsch, Ernoe; Diederich, Francois; Alvarado, Robert J.; Echegoyen, Luis; Nunez, Ignacio Perez
Helvetica Chimica Acta, 2002 , vol. 85, # 7 p. 2009 - 2055
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 24 h;
参考文献
Allwood, Billy L.; Kohnke, Franz H.; Slawin, Alexandra M. Z.; Stoddart, J. Fraser; Williams, David J.
Journal of the Chemical Society, Chemical Communications, 1985 , # 6 p. 311 - 314
反应条件
sodium methylate in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=150°C; 0.0233333 h;
参考文献
Imakura; Okimoto; Konishi; Hisazumi; Yamazaki; Kobayashi; Yamashita
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 7 p. 1691 - 1696
反应条件
phosphoric acid T=0°C; 0.5 h; Yield given;
参考文献
Nakazato, Atsuro; Ohta, Kohmei; Sekiguchi, Yoshinori; Okuyama, Shigeru; Chaki, Shigeyuki; Kawashima, Yutaka; Hatayama, Katsuo
Journal of Medicinal Chemistry, 1999 , vol. 42, # 6 p. 1076 - 1087
反应条件
1: K2CO3 / dimethylformamide / 24 h / Ambient temperature 2: H3PO4 / 0.5 h / 0 °C View Scheme
参考文献
Nakazato, Atsuro; Ohta, Kohmei; Sekiguchi, Yoshinori; Okuyama, Shigeru; Chaki, Shigeyuki; Kawashima, Yutaka; Hatayama, Katsuo
Journal of Medicinal Chemistry, 1999 , vol. 42, # 6 p. 1076 - 1087
反应条件
1: K2CO3 / dimethylformamide / 24 h / Ambient temperature 2: H3PO4 / 0.5 h / 0 °C View Scheme
参考文献
Nakazato, Atsuro; Ohta, Kohmei; Sekiguchi, Yoshinori; Okuyama, Shigeru; Chaki, Shigeyuki; Kawashima, Yutaka; Hatayama, Katsuo
Journal of Medicinal Chemistry, 1999 , vol. 42, # 6 p. 1076 - 1087
