1,2,3,4,5-五甲基环戊二烯合成路线 （共 113 条）
反应条件
triphenylphosphine in tetrachloromethane 0.333333 h; Heating;
参考文献
Burger, Ulrich; Etienne, Robert
Helvetica Chimica Acta, 1984 , vol. 67, p. 2057 - 2062
反应条件
trichloroacetic acid in dichloromethane T=25 - 30°C; 12 h;
参考文献
Uemura, Minoru; Yagi, Kazunari; Iwasaki, Masayuki; Nomura, Kenichi; Yorimitsu, Hideki; Oshima, Koichiro
Tetrahedron, 2006 , vol. 62, # 15 p. 3523 - 3535
反应条件
1.1: 2,3-dichloro-5,6-dicyanobenzoquinone / toluene / 24 h / 110 °C 2.1: n-butyllithium / hexane; tetrahydrofuran / cooling 2.2: hexane; tetrahydrofuran / -20 °C 2.3: tetrahydrofuran; hexane; diethyl ether / -20 °C 3.1: trichloroacetic acid / CH2Cl2 / 0.75 h / 25 - 30 °C 4.1: trichloroacetic acid / CH2Cl2 / 0.5 h / 25 - 30 °C 5.1: n-butyllithium / hexane; tetrahydrofuran / -78 - 20 °C 5.2: 85 percent / tetrahydrofuran; hexane / 1 h / -20 °C 6.1: trichloroacetic acid / CH2Cl2 / 1.5 h / 28 °C View Scheme
参考文献
Uemura, Minoru; Yagi, Kazunari; Iwasaki, Masayuki; Nomura, Kenichi; Yorimitsu, Hideki; Oshima, Koichiro
Tetrahedron, 2006 , vol. 62, # 15 p. 3523 - 3535
反应条件
2: MnO2 / pentane 3: HCO2H, H3PO4 4: (i), (ii) I2 View Scheme
参考文献
deVries,L.
Journal of Organic Chemistry, 1960 , vol. 25, p. 1838
反应条件
1: MnO2 / pentane 2: HCO2H, H3PO4 3: (i), (ii) I2 View Scheme
参考文献
deVries,L.
Journal of Organic Chemistry, 1960 , vol. 25, p. 1838
反应条件
K12Ga4[N,N'-bis(2,3-dihydroxybenzoyl)-1,5-diaminonapthalene]6 in D20 T=20°C; Nazarov cyclization; 3 h; regioselective reaction;
参考文献
Hastings, Courtney J.; Bergman, Robert G.; Raymond, Kenneth N.
Chemistry - A European Journal, 2014 , vol. 20, # 14 p. 3966 - 3973
反应条件
K12Ga4[N,N'-bis(2,3-dihydroxybenzoyl)-1,5-diaminonapthalene]6 in D20 T=20°C; Nazarov cyclization; 3 h; regioselective reaction;
参考文献
Hastings, Courtney J.; Backlund, Mikael P.; Bergman, Robert G.; Raymond, Kenneth N.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 45 p. 10570 - 10573
反应条件
K12Ga4[N,N'-bis(2,3-dihydroxybenzoyl)-1,5-diaminonapthalene]6 in D20 T=20°C; Nazarov cyclization; 3 h; regioselective reaction;
参考文献
Hastings, Courtney J.; Backlund, Mikael P.; Bergman, Robert G.; Raymond, Kenneth N.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 45 p. 10570 - 10573
反应条件
1: diethyl ether / -78 - 20 °C 2: silica gel / benzene-d6 / 0.08 h / 45 °C View Scheme
参考文献
Hastings, Courtney J.; Backlund, Mikael P.; Bergman, Robert G.; Raymond, Kenneth N.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 45 p. 10570 - 10573
反应条件
toluene-4-sulfonic acid in ethylene glycol
参考文献
Davies, Alwyn G.; Lusztyk, Janusz
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 692 - 696
