3-溴-2-苯基-咪唑并[1,2-a]吡啶合成路线 （共 9 条）
反应条件
sodium azide; CuCl2·2H2O; potassium carbonate in N,N-dimethyl-formamide T=150°C; 24 h;
参考文献
Pericherla, Kasiviswanadharaju; Jha, Amitabh; Khungar, Bharti; Kumar, Anil
Organic Letters, 2013 , vol. 15, # 17 p. 4304 - 4307
反应条件
N-bromosuccinmide in acetonitrile
T=20°C; 2 h;
参考文献
Marhadour, Sophie; Bazin, Marc-Antoine; Marchand, Pascal
Tetrahedron Letters, 2012 , vol. 53, # 3 p. 297 - 300
反应条件
N-bromosuccinmide; sodium hydrogencarbonate in N,N-dimethyl-formamide
T=50 - 70°C;
参考文献
Salgado-Zamora, Hector; Velazquez, Manuel; Mejia, Daniel; Campos-Aldrete; Jimenez, Rogelio; Cervantes, Humberto
Heterocyclic Communications, 2008 , vol. 14, # 1-2 p. 27 - 32
反应条件
1.1: ethanol / 18.5 h / 0 °C / Reflux
1.2: 12 h / Reflux
2.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethylene glycol dimethyl ether; water / 4 h / 100 °C / Inert atmosphere; Sealed vessel
3.1: N-bromosuccinmide / acetonitrile / 2 h / 20 °C
View Scheme
参考文献
Marhadour, Sophie; Bazin, Marc-Antoine; Marchand, Pascal
Tetrahedron Letters, 2012 , vol. 53, # 3 p. 297 - 300
反应条件
potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride
T=20°C;
参考文献
Khlebnikov, A. F.; Kostik, E. I.; Kostikov, R. R.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 6 p. 636 - 642
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , vol. 27, # 6 p. 810 - 816
反应条件
1: trichlorophosphate / toluene / 16 h / Reflux
2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethylene glycol dimethyl ether; water / 6 h / Inert atmosphere; Sealed vessel; Reflux
3: N-bromosuccinmide / acetonitrile / 2 h / 20 °C
View Scheme
参考文献
Marhadour, Sophie; Bazin, Marc-Antoine; Marchand, Pascal
Tetrahedron Letters, 2012 , vol. 53, # 3 p. 297 - 300
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethylene glycol dimethyl ether; water / 6 h / Inert atmosphere; Sealed vessel; Reflux
2: N-bromosuccinmide / acetonitrile / 2 h / 20 °C
View Scheme
参考文献
Marhadour, Sophie; Bazin, Marc-Antoine; Marchand, Pascal
Tetrahedron Letters, 2012 , vol. 53, # 3 p. 297 - 300
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethylene glycol dimethyl ether; water / 4 h / 100 °C / Inert atmosphere; Sealed vessel
2: N-bromosuccinmide / acetonitrile / 2 h / 20 °C
View Scheme
参考文献
Marhadour, Sophie; Bazin, Marc-Antoine; Marchand, Pascal
Tetrahedron Letters, 2012 , vol. 53, # 3 p. 297 - 300
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethylene glycol dimethyl ether; water / 6 h / Inert atmosphere; Sealed vessel; Reflux
2: N-bromosuccinmide / acetonitrile / 2 h / 20 °C
View Scheme
参考文献
Marhadour, Sophie; Bazin, Marc-Antoine; Marchand, Pascal
Tetrahedron Letters, 2012 , vol. 53, # 3 p. 297 - 300
