2-(噻吩-2-基)乙基对甲苯磺酸酯合成路线 （共 14 条）
反应条件
sodium hydrogencarbonate; potassium iodide in acetonitrile 12 h; Reflux;
参考文献
Ferraboschi, Patrizia; Mieri, Maria De; Galimberti, Fiorella
Tetrahedron Asymmetry, 2010 , vol. 21, # 17 p. 2136 - 2141
反应条件
triethylamine T=78 - 82°C; 8 - 10 h; Product distribution / selectivity;
参考文献
ORCHID CHEMICALS and PHARMACEUTICALS LIMITED
Patent: WO2007/144729 A1, 2007 ;
Location in patent: Page/Page column 5; 8 ;
反应条件
1.1: sodium hydrogencarbonate / toluene / 25 - 30 °C 1.2: 85 - 90 °C 2.1: water / 25 - 35 °C 2.2: pH 7 - 8 3.1: sulfuric acid / acetone; methanol / 0 - 30 °C View Scheme
参考文献
ORCHID CHEMICALS AND PHARMACEUTICALS LTD; RAO, Jagadeeshwar; NANDAM, Harikrishna; REDAMALLA, Anjireddy; REGURI, Buchi, Reddy
Patent: WO2011/12961 A1, 2011 ;
反应条件
in N,N-dimethyl-formamide
T=85°C; 2 h;
参考文献
Meth-Cohn, Otto; Vij, Rup Rani; Smalley, Robert K.; Bass, Robert J.
Journal of Chemical Research, Miniprint, 1989 , # 5 p. 1001 - 1018
