2-(2-噻吩基)喹喔啉合成路线 （共 19 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in toluene
T=80°C; 4 h;
参考文献
Neochoritis, Constantinos; Stephanidou-Stephanatou, Julia; Tsoleridis, Constantinos A.
Synlett, 2009 , # 2 p. 302 - 305
反应条件
chloranil in benzene
T=80°C; 5 h;
参考文献
Kauffmann, Thomas; Ghanem, Mohammad; Otter, Rolf
Chemische Berichte, 1982 , vol. 115, # 2 p. 459 - 466
反应条件
acetic acid
6 h; Heating;
参考文献
Gazit, Aviv; App, Harald; McMahon, Gerald; Chen, Jefferey; Levitzki, Alexander; Bohmer, Frank D.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 11 p. 2170 - 2177
反应条件
1: 60 percent
2: 85 percent / dimethyl dioxirane / acetone / Ambient temperature
3: ethanol / Ambient temperature
View Scheme
参考文献
Ihmels; Maggini; Prato; Scorrano
Tetrahedron Letters, 1991 , vol. 32, # 43 p. 6215 - 6218
反应条件
1: 85 percent / dimethyl dioxirane / acetone / Ambient temperature
2: ethanol / Ambient temperature
View Scheme
参考文献
Ihmels; Maggini; Prato; Scorrano
Tetrahedron Letters, 1991 , vol. 32, # 43 p. 6215 - 6218
反应条件
1: copper(II) oxide; iodine / methanol / |Reflux
2: K3PO4*3H2O / 12 h / 40 °C
View Scheme
参考文献
Lian, Mi; Li, Qi; Zhu, Yanping; Yin, Guodong; Wu, Anxin
Tetrahedron, 2012 , vol. 68, # 47 p. 9598 - 9605
反应条件
1: 1) 2M BuLi / 1) THF, ether, hexane, 1,5 h, 0-10 deg C, 2) THF, ether, hexane, -70 to -65 deg C, 17 h
2: 88 percent / KMnO4 / acetone / 35 - 40 °C
View Scheme
参考文献
Kauffmann, Thomas; Ghanem, Mohammad; Otter, Rolf
Chemische Berichte, 1982 , vol. 115, # 2 p. 459 - 466
反应条件
in ethanol
Ambient temperature;
参考文献
Ihmels; Maggini; Prato; Scorrano
Tetrahedron Letters, 1991 , vol. 32, # 43 p. 6215 - 6218
参考文献
Druey; Hueni
Helvetica Chimica Acta, 1952 , vol. 35, p. 2301,2308
