2-羟基-4-甲基戊酸甲酯合成路线 （共 6 条）
反应条件
lithium hydroxide in tetrahydrofuran 3 h; Ambient temperature;
参考文献
Mikami, Koichi; Terada, Masahiro; Nakai, Takeshi
Journal of the American Chemical Society, 1990 , vol. 112, # 10 p. 3949 - 3954
反应条件
TiCl2(OPri)2; 4 A molecular sieve; hydrogen; (R)-2,2'-dihydroxy-1,1'-binaphthyl; platinum(IV) oxide
1.) CH2Cl2, -30 deg C, 8 h, 2.) ethyl acetate, RT, 1 d; Yield given. Multistep reaction;
参考文献
Mikami, Koichi; Terada, Masahiro; Nakai, Takeshi
Journal of the American Chemical Society, 1990 , vol. 112, # 10 p. 3949 - 3954
反应条件
1: 4N H2SO4 / 24 h / Heating
View Scheme
参考文献
Kelly, T. Ross; Arvanitis, Argyrios
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 39 - 42
参考文献
Kelly, T. Ross; Arvanitis, Argyrios
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 39 - 42
反应条件
tert.-butylnitrite; water; iodine; acetic acid in dichloromethane
T=0 - 20°C; Inert atmosphereDarkness; ReactivityMechanism; Reagent/catalyst;
参考文献
Werardo, Giancarlo; Geatti, Paola; Gambi, Alberto
Journal of Physical Organic Chemistry, 2009 , vol. 22, # 1 p. 24 - 30
反应条件
1: Et3N, 4-N,N-dimethylaminopyridine / various solvent(s) / 6 h / 60 °C
2: 60 percent / potassium fluoride / formamide / 2.5 h / 80 °C / 10 Torr
3: 90 percent / formic acid
View Scheme
参考文献
Fritz-Langhals, Elke; Schuetz, Gabi
Tetrahedron Letters, 1993 , vol. 34, # 2 p. 293 - 296
