2-庚基-1,4-二氢-4-氧代-3-喹啉甲醛合成路线 （共 6 条）
反应条件
hydrogenchloride; trifluoroacetic acid in methanol; water
反应条件
1: Duff formylation; 2: With water; trifluoroacetic acid Duff formylation;
参考文献
Tetrahedron Letters, , vol. 51, # 45 p. 5919 - 5921
反应条件
1.1: pyridine / dichloromethane / 0 - 20 °C / |Inert atmosphere 2.1: 5 h / |Reflux 3.1: |Reflux 4.1: diphenylether / 2.5 h / 270 °C 4.2: 18 h / 20 °C 5.1: ammonium hydroxide / water; ethyl acetate 6.1: trifluoroacetic acid / |Inert atmosphere; |Reflux 6.2: 2.5 h / |Inert atmosphere; |Reflux 6.3: 1.5 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 44 p. 8903 - 8910
反应条件
1.1: 5 h / |Reflux 2.1: |Reflux 3.1: diphenylether / 2.5 h / 270 °C 3.2: 18 h / 20 °C 4.1: ammonium hydroxide / water; ethyl acetate 5.1: trifluoroacetic acid / |Inert atmosphere; |Reflux 5.2: 2.5 h / |Inert atmosphere; |Reflux 5.3: 1.5 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 44 p. 8903 - 8910
反应条件
1.1: |Reflux 2.1: diphenylether / 2.5 h / 270 °C 2.2: 18 h / 20 °C 3.1: ammonium hydroxide / water; ethyl acetate 4.1: trifluoroacetic acid / |Inert atmosphere; |Reflux 4.2: 2.5 h / |Inert atmosphere; |Reflux 4.3: 1.5 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 44 p. 8903 - 8910
反应条件
1.1: ammonium hydroxide / water; ethyl acetate 2.1: trifluoroacetic acid / |Inert atmosphere; |Reflux 2.2: 2.5 h / |Inert atmosphere; |Reflux 2.3: 1.5 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 44 p. 8903 - 8910
