5-苯基-3-三氟甲基吡唑合成路线 （共 23 条）
反应条件
sulfuric acid T=130°C; 5 h;
参考文献
Ermolenko, Mikhail S.; Guillou, Sandrine; Janin, Yves L.
Tetrahedron, 2013 , vol. 69, # 1 p. 257 - 263
反应条件
1: With NH2NH2•xH2O in ethanol Reflux; 2: With hydrogenchloride; water 0.0166667 h; Reflux;
参考文献
Ermolenko, Mikhail S.; Guillou, Sandrine; Janin, Yves L.
Tetrahedron, 2013 , vol. 69, # 1 p. 257 - 263
反应条件
hydrazine hydrate in ethanol T=60°C; 2 h;
参考文献
Yu, Hong-Bin; Huang, Wei-Yuan
Journal of Fluorine Chemistry, 1997 , vol. 84, # 1 p. 65 - 67
反应条件
hydrazine hydrate in ethanol T=60°C; 2 h;
参考文献
Yu, Hong-Bin; Huang, Wei-Yuan
Journal of Fluorine Chemistry, 1998 , vol. 87, # 1 p. 69 - 73
反应条件
1: 3,3,3-trifluoro-1-propyne With n-butyllithium in tetrahydrofuran T=-78°C; 0.5 h; 2: N-Methoxy-N-methyl-benzamide in tetrahydrofuran T=-78 - 0°C; 3: With water; hydrazine in tetrahydrofuran
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Myong Sang; Kim, Bum Tae
Journal of Fluorine Chemistry, 2004 , vol. 125, # 11 SPEC. ISS. p. 1629 - 1638
反应条件
toluene-4-sulfonic acid in ethanol T=78°C; 15 h; SolventReagent/catalystConcentration; regioselective reaction;
参考文献
Martins, Marcos A. P.; Marzari, Mara R. B.; Frizzo, Clarissa P.; Zanatta, Marcileia; Buriol, Lilian; Andrade, Valquiria P.; Zanatta, Nilo; Bonacorso, Helio G.
European Journal of Organic Chemistry, 2012 , # 36 p. 7112 - 7119
反应条件
hydrazine in benzene Heating;
参考文献
Linderman, Russell J.; Kirollos, S. Kirollos
Tetrahedron Letters, 1989 , vol. 30, # 16 p. 2049 - 2052
反应条件
hydrazine hydrate in ethanol 4 h; Heating;
参考文献
Tang, Xiao-Qing; Hu, Chang-Ming
Journal of Fluorine Chemistry, 1995 , vol. 73, # 2 p. 129 - 132
反应条件
hydrazine hydrate in ethanol 12 h; Heating;
参考文献
Tang; Hu
Journal of the Chemical Society - Series Chemical Communications, 1994 , # 5 p. 631 - 632
反应条件
ammonium cerium (IV) nitrate in water; acetonitrile T=20°C; 22 h; Cooling with ice;
参考文献
Foster, Robert S.; Adams, Harry; Jakobi, Harald; Harrity, Joseph P. A.
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 4049 - 4064
