6-脱氧-6-碘-1,2:3,4-二-o-异亚丙基-α-d-半乳糖吡喃糖苷合成路线 （共 31 条）
反应条件
1: 91 percent / NaH / hexamethylphosphoric acid triamide / 2 h / Ambient temperature 2: 83 percent / Hg(OAc)2 / acetone; H2O / 0.25 h / 0 °C 3: 73 percent / DMAP / pyridine / 4 h / Ambient temperature 4: 95 percent / CeCl3*7H2O, NaBH4 / methanol / 0.67 h / -78 °C 5: 20 percent / DMAP / pyridine / 6 h / Ambient temperature 6: 1.) NaOMe, 2.) conc. HCl / 1.) methanol, room temperature, 15 min, 2.) room temperature, 15 min View Scheme
参考文献
Mereyala, Hari Babu; Gaddam, Reddy
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 15 p. 2187 - 2190
反应条件
hypophosphorous acid; triethylamine; Vazo44 in isopropyl alcohol T=80°C; 0.5 h;
参考文献
Nambu, Hisanori; Alinejad, Anahita Hessamian; Hata, Kayoko; Fujioka, Hiromichi; Kita, Yasuyuki
Tetrahedron Letters, 2004 , vol. 45, # 48 p. 8927 - 8929
反应条件
copper diacetate in benzene Heating; Yields of byproduct given;
参考文献
Vismara, Elena; Donna, Angela; Minisci, Francesco; Naggi, Annamaria; Pastori, Nadia; Torri, Giangiacomo
Journal of Organic Chemistry, 1993 , vol. 58, # 4 p. 959 - 963
反应条件
dibenzoyl peroxide in acetonitrile Heating; Yields of byproduct given;
参考文献
Vismara, Elena; Donna, Angela; Minisci, Francesco; Naggi, Annamaria; Pastori, Nadia; Torri, Giangiacomo
Journal of Organic Chemistry, 1993 , vol. 58, # 4 p. 959 - 963
反应条件
iodine; magnesium in tetrahydrofuran 6 h; Heating;
参考文献
Ariatti, Mario; Zemlicka, Jiri
Journal of Organic Chemistry, 1981 , vol. 46, p. 5204 - 5212
反应条件
2,2'-azo-bisisobutyronitrile; tributyltin chloride; sodium cyanoborohydride in tert-butyl alcohol 4 h; Heating;
参考文献
Gomez, Ana M.; Lopez, J. Cristobal; Fraser-Reid, Bert
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 13 p. 1689 - 1696
反应条件
trifluoroacetic acid; dibenzoyl peroxide in acetonitrile Heating; Yield given;
参考文献
Vismara, Elena; Donna, Angela; Minisci, Francesco; Naggi, Annamaria; Pastori, Nadia; Torri, Giangiacomo
Journal of Organic Chemistry, 1993 , vol. 58, # 4 p. 959 - 963
反应条件
trifluoroacetic acid; dibenzoyl peroxide in acetonitrile Heating; Yield given. Yields of byproduct given;
参考文献
Vismara, Elena; Donna, Angela; Minisci, Francesco; Naggi, Annamaria; Pastori, Nadia; Torri, Giangiacomo
Journal of Organic Chemistry, 1993 , vol. 58, # 4 p. 959 - 963
反应条件
trifluoroacetic acid; dibenzoyl peroxide in acetonitrile Heating; Yield given. Yields of byproduct given;
参考文献
Vismara, Elena; Donna, Angela; Minisci, Francesco; Naggi, Annamaria; Pastori, Nadia; Torri, Giangiacomo
Journal of Organic Chemistry, 1993 , vol. 58, # 4 p. 959 - 963
反应条件
pyridine; samarium diiodide; acetic anhydride 1) THF, HMPA, -78 deg C; Yield given. Multistep reaction;
参考文献
Chiara, Jose Luis; Martinez, Sonia; Bernabe, Manuel
Journal of Organic Chemistry, 1996 , vol. 61, # 19 p. 6488 - 6489
