反应条件
1: LiAH4 / diethyl ether / 1 h / Ambient temperature
2: MnO2 / CH2Cl2 / 3 h / Ambient temperature
3: toluene; H2O / 1 h / 90 °C
4: 2.) silica gel / 1.) toluene, 100 deg C, 3 h; 2.) 80 deg c, 6 h
5: 1.) LiAlH4; 2.) TsOH / 1.) Et2O, room temperature, 1 h; 2.) toluene, reflux, 1 h
View Scheme
参考文献
Snowden, Roger L.; Linder, Simon M.; Wuest, Manfred
Helvetica Chimica Acta, 1989 , vol. 72, p. 892 - 905
