ethyl bromide; diethyl ether; magnesium Behandeln des Reaktionsgemisches mit Kohlendioxid;

1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine; triphenylphosphine / tetrahydrofuran 2: methanol; potassium carbonate View Scheme

n-butyllithium in tetrahydrofuran; hexane soln. of n-BuLi in hexane added at -78°C under Ar to soln. of C4HSMe2I on THF; react. mixt. stirred at this temp. for 30 min and Bu3B then added with additional stirring for 1 h; mixt. slow heated, cooled to 0°C ...; NaOH added ...; ppt. filtered off, washed with small amt. and dried in desiccator; elem.anal.;

iodine; iodic acid; acetic acid in chloroform 2.5 h; Reflux;

sodium chloride; sulfuric acid; iodine; acetic acid in sodium hydroxide; water; ethyl acetate

(i) PhLi, Et2O, (ii) /BRN= 635994/; Multistep reaction;