萘并(1,2-d)噻唑-2-胺合成路线 （共 12 条）
反应条件
sodium azide; phosphoric acid; sulfuric acid; sodium nitrite
参考文献
Liu, Kang-Chien; Shih, Bi-Jane
Archiv der Pharmazie (Weinheim, Germany), 1985 , vol. 318, # 3 p. 283 - 285
反应条件
iodine; oxygen; toluene-4-sulfonic acid in dimethyl sulfoxide
T=75°C; P=760.051 Torr; 24 h;
参考文献
Zhao, Jinwu; Huang, Huawen; Wu, Wanqing; Chen, Huoji; Jiang, Huanfeng
Organic Letters, 2013 , vol. 15, # 11 p. 2604 - 2607
参考文献
Liu; Lee; Shih; Chen; Tao
Archiv der Pharmazie, 1982 , vol. 315, # 10 p. 872 - 877
反应条件
bromine; acetic acid
T=25 - 35°C; 20 h;
参考文献
Moradi Rufchahi; Yousefi, Hessamoddin; Mohammadinia, Mojgan
Journal of Molecular Liquids, 2013 , vol. 188, p. 173 - 177
参考文献
Ubaldini; Fiorenza
Gazzetta Chimica Italiana, 1946 , vol. 76, p. 215,221
反应条件
hydrogenchloride
T=130°C; im Rohr;
参考文献
Freund
Chemische Berichte, 1891 , vol. 24, p. 4187
反应条件
1: 2.) 2 N NaOH / 1.) acetone, 50 deg C 2.) reflux
2: 1.) bromine, AcOH 2.) 25percent NH4OH / 1.) room temp. 2.) room temp.
View Scheme
参考文献
Kajino; Mizuno; Tawada; Shibouta; Nishikawa; Meguro
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2888 - 2895
反应条件
nitrosyl-sulphuric acid; sulfuric acid
参考文献
Gorelik,M.V.; Lomzakova,V.I.
Zhurnal Organicheskoi Khimii, 1978 , vol. 14, # 5 p. 1051 - 1055,981 - 985
参考文献
Liu; Lee; Shih; Chen; Tao
Archiv der Pharmazie, 1982 , vol. 315, # 10 p. 872 - 877
反应条件
O-(2,4,6-trimethylbenzenesulfonyl)hydroxylamine in dichloromethane
参考文献
Liu; Shih; Lee
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1331 - 1335
