1: 1.) Bu3P, 2.) CH3I / 1.) THF, 1 h, 2.) THF, 1 h, 3.) THF, 5 min 2: 96 percent / tetrahydrofuran; diethyl ether / 0.5 h / -10 °C 3: 81 percent / Bu4NF / tetrahydrofuran / 3 h / Heating 4: Heating 5: 82 percent / m-chloroperbenzoic acid, KF / CH2Cl2 / 1 h 6: 1.) Ts-NH-NH2, 2.) (Ph3P)2CuBH4 / 1.) MeOH, reflux, 40 min, 2.) CHCl3, reflux, 4h View Scheme

1: (i) NaH, (ii) /BRN= 1209245/ 2: (decarboxylation) 3: NaH View Scheme

1: KOtBu / 2-methyl-propan-2-ol 2: aq. KOH / ethanol View Scheme

tetra(n-butyl)ammonium hydroxide in chloroform; water 0.25 h;

sodium bromide electrolysis;

(i) NaH, benzene, (ii) /BRN= 507487/; Multistep reaction;