4-甲基-1H-吡咯-3-甲腈合成路线 (共 4 条)
反应条件
sodium hydroxide in water
T=20°C; 12 h; Inert atmosphere;
参考文献
Dawadi, Prativa B. S.; Lugtenburg, Johan
European Journal of Organic Chemistry, 2008 , # 13 p. 2288 - 2292
反应条件
sodium hydride in tetrahydrofuran
1 h; Reflux;
参考文献
GLAXO GROUP LIMITED
Patent: WO2009/109608 A1, 2009 ;
Location in patent: Page/Page column 77 ;
WO 2009/109608 A1
反应条件
potassium tert-butylate in tetrahydrofuran
Heating;
参考文献
Katritzky, Alan R.; Cheng, Dai; Musgrave, Richard P.
Heterocycles, 1997 , vol. 44, # 1 p. 67 - 70
反应条件
1 h; Inert atmosphereReflux;
参考文献
Dawadi, Prativa B. S.; Lugtenburg, Johan
European Journal of Organic Chemistry, 2008 , # 13 p. 2288 - 2292