2-(4-(苄氧基)苯基)乙醛合成路线 （共 13 条）
反应条件
Dess-Martin periodane in dichloromethane 1.33333 h;
参考文献
Aberle, Nicholas; Catimel, Jenny; Nice, Edouard C.; Watson, Keith G.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 13 p. 3741 - 3744
反应条件
1.1: BH3*DMS / tetrahydrofuran / 4 h / 20 °C 1.2: 88 percent / H2O2; NaOH / tetrahydrofuran; H2O; ethanol / 3 h / 20 °C 2.1: oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - -60 °C View Scheme
参考文献
Jiang, Gaoxi; Chen, Jian; Thu, Hung-Yat; Huang, Jie-Sheng; Zhu, Nianyong; Che, Chi-Ming
Angewandte Chemie - International Edition, 2008 , vol. 47, # 35 p. 6638 - 6642
反应条件
1: 99 percent / K2CO3 / dimethylformamide / 24 h / 65 °C 2: 97 percent / Dess-Martin periodinane / CH2Cl2 / 1.33 h View Scheme
参考文献
Nadkarni, Dwayaja H.; Murugesan, Srinivasan; Velu, Sadanandan E.
Tetrahedron, 2013 , vol. 69, # 20 p. 4105 - 4113
反应条件
1: 99 percent / K2CO3 / dimethylformamide / 24 h / 65 °C 2: 97 percent / Dess-Martin periodinane / CH2Cl2 / 1.33 h View Scheme
参考文献
Aberle, Nicholas; Catimel, Jenny; Nice, Edouard C.; Watson, Keith G.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 13 p. 3741 - 3744
反应条件
1.1: 78 percent / sodium amide / tetrahydrofuran / 24 h / 20 °C 2.1: BH3*DMS / tetrahydrofuran / 4 h / 20 °C 2.2: 88 percent / H2O2; NaOH / tetrahydrofuran; H2O; ethanol / 3 h / 20 °C 3.1: oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - -60 °C View Scheme
参考文献
Fernandes, Rodney A; Bodas, Mandar S; Kumar, Pradeep
Tetrahedron, 2002 , vol. 58, # 6 p. 1223 - 1227
反应条件
1.1: 99 percent / K2CO3; TBAI / dimethylformamide / 24 h / 20 °C 2.1: 78 percent / sodium amide / tetrahydrofuran / 24 h / 20 °C 3.1: BH3*DMS / tetrahydrofuran / 4 h / 20 °C 3.2: 88 percent / H2O2; NaOH / tetrahydrofuran; H2O; ethanol / 3 h / 20 °C 4.1: oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - -60 °C View Scheme
参考文献
Takaoka, Eiji; Yoshikawa, Naoki; Yamada, Yoichi M.A.; Sasai, Hiroaki; Shibasaki, Masakatsu
Heterocycles, 1997 , vol. 46, # 1 p. 157 - 163
反应条件
1.1: 99 percent / K2CO3; TBAI / dimethylformamide / 24 h / 20 °C 2.1: 78 percent / sodium amide / tetrahydrofuran / 24 h / 20 °C 3.1: BH3*DMS / tetrahydrofuran / 4 h / 20 °C 3.2: 88 percent / H2O2; NaOH / tetrahydrofuran; H2O; ethanol / 3 h / 20 °C 4.1: oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - -60 °C View Scheme
参考文献
Fernandes, Rodney A; Bodas, Mandar S; Kumar, Pradeep
Tetrahedron, 2002 , vol. 58, # 6 p. 1223 - 1227
反应条件
hydrogenchloride in water; acetone 1 h; Reflux;
参考文献
Ermolat'Ev, Denis S.; Bariwal, Jitender B.; Steenackers, Hans P. L.; De Keersmaecker, Sigrid C. J.; Van Der Eycken, Erik V.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 49 p. 9465 - 9468
反应条件
1.1: toluene / 20 h / Molecular sieve; Reflux 2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 15.5 h / 0 - 20 °C 2.2: 36 h / 7600.51 Torr View Scheme
参考文献
Tilley, Andrew J.; Zanatta, Shannon D.; Qin, Cheng Xue; Kim, In-Kyeom; Seok, Young-Mi; Stewart, Alastair; Woodman, Owen L.; Williams, Spencer J.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2353 - 2361
反应条件
1.1: toluene / 20 h / Molecular sieve; Reflux 2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 15.5 h / 0 - 20 °C 2.2: 36 h / 7600.51 Torr View Scheme
参考文献
Tilley, Andrew J.; Zanatta, Shannon D.; Qin, Cheng Xue; Kim, In-Kyeom; Seok, Young-Mi; Stewart, Alastair; Woodman, Owen L.; Williams, Spencer J.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2353 - 2361
