5-(3-甲基苯基)-2-糠酸合成路线 （共 4 条）
反应条件
1: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride in isopropyl alcohol 5 h; RefluxInert atmosphere; 2: With water; sodium hydroxide in methanol T=20°C; 3: With hydrogenchloride in methanol; water pH=2 - 3;
参考文献
WO2011/94890 A1, ;
Page/Page column 124-125 ;
WO 2011/094890 A1
反应条件
lithium hydroxide in tetrahydrofuran
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3258 - 3261
反应条件
1: Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane / 100 °C 2: aq. LiOH / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3258 - 3261
反应条件
1: Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane / 100 °C 2: aq. LiOH / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3258 - 3261
