1-(4-氟苯基)-4-[(4-甲基苯基)磺酰基]-哌嗪合成路线 (共 3 条)
反应条件
hydrogen bromide; phenol 0.5 h; Heating;
参考文献
Collins, Michael; Lasne, Marie-Claire; Barre, Louisa
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 23 p. 3185 - 3188
反应条件
1: 66 percent / 48percent aq. HBr, phenol / 0.5 h / Heating 2: 77 percent / NEt3 / dimethylformamide / 0.33 h / 110 °C View Scheme
参考文献
Collins, Michael; Lasne, Marie-Claire; Barre, Louisa
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 23 p. 3185 - 3188
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; sodium hydrogencarbonate
T=130°C; 1 h;
参考文献
Collins, Michael; Lasne, Marie-Claire; Barre, Louisa
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 23 p. 3185 - 3188