1-(2-甲氧基苯基)乙胺合成路线 （共 33 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; P=760 Torr; 12 h;
参考文献
Kuendig, E. Peter; Botuha, Candice; Lemercier, Gilles; Romanens, Patrick; Saudan, Lionel; Thibault, Sylvie
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 561 - 579
反应条件
5 Pd(II)/C(eggshell); hydrogen in methanol T=50°C; P=11251.1 Torr; 24 h; optical yield given as percent ee;
参考文献
Nugent, Thomas C.; Negru, Daniela E.; El-Shazly, Mohamed; Hu, Dan; Sadiq, Abdul; Bibi, Ahtaram; Umar, M. Naveed
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 2085 - 2092
反应条件
hexacarbonyl molybdenum in water; acetonitrile T=85°C; 1 h;
参考文献
Atobe, Masakazu; Yamazaki, Naoki; Kibayashi, Chihiro
Journal of Organic Chemistry, 2004 , vol. 69, # 17 p. 5595 - 5607
反应条件
1: 99 percent / (S)-oxazaborolidine; BH3*THF / tetrahydrofuran; toluene / 4 h / 20 °C 2: 59 percent / diphenylphosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 12 h / 20 °C 3: 76 percent / H2 / Pd/C / ethanol / 12 h / 20 °C / 760 Torr View Scheme
参考文献
Nugent, Thomas C.; Negru, Daniela E.; El-Shazly, Mohamed; Hu, Dan; Sadiq, Abdul; Bibi, Ahtaram; Umar, M. Naveed
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 2085 - 2092
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 456 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Queyroy, Severine; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1759 - 1764
反应条件
1: 59 percent / diphenylphosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 12 h / 20 °C 2: 76 percent / H2 / Pd/C / ethanol / 12 h / 20 °C / 760 Torr View Scheme
参考文献
Kuendig, E. Peter; Botuha, Candice; Lemercier, Gilles; Romanens, Patrick; Saudan, Lionel; Thibault, Sylvie
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 561 - 579
反应条件
2: phosphate buffer (pH 7.0) / acetone / lipase B from Candida antarctica in the immobilised form Novozym 435 3: OH(-), H2O View Scheme
参考文献
Chapman, Daniel T.; Crout, David H. G.; Mahmoudian, Mahmoud; Scopes, David I. C.; Smith, Paul W.
Chemical Communications, 1996 , # 21 p. 2415 - 2416
反应条件
1: phosphate buffer (pH 7.0) / acetone / lipase B from Candida antarctica in the immobilised form Novozym 435 2: OH(-), H2O View Scheme
参考文献
Chapman, Daniel T.; Crout, David H. G.; Mahmoudian, Mahmoud; Scopes, David I. C.; Smith, Paul W.
Chemical Communications, 1996 , # 21 p. 2415 - 2416
反应条件
1: toluene; diethyl ether / 0.42 h / -20 °C 2: 74 percent / Mo(CO)6 / acetonitrile; H2O / 1 h / 85 °C View Scheme
参考文献
Atobe, Masakazu; Yamazaki, Naoki; Kibayashi, Chihiro
Journal of Organic Chemistry, 2004 , vol. 69, # 17 p. 5595 - 5607
反应条件
1: 97 percent / TsOH / toluene / 0.5 h / Heating 2: toluene; diethyl ether / 0.42 h / -20 °C 3: 74 percent / Mo(CO)6 / acetonitrile; H2O / 1 h / 85 °C View Scheme
参考文献
Atobe, Masakazu; Yamazaki, Naoki; Kibayashi, Chihiro
Journal of Organic Chemistry, 2004 , vol. 69, # 17 p. 5595 - 5607
