water; AgCl 0.333333 h; Heating;

water

sodium hydroxide; acetic acid; aniline in methanol; water; toluene

1: in DMF (N,N-dimethyl-formamide) T=55°C; 1 h; 2: With sodium acetate T=85°C; 4 h;

methanol

Stage #1: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098280', constants.ctx, '0')">tert.-butylhydroperoxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3924762', constants.ctx, '0')">potassium hydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11343039', constants.ctx, '0')">DMF (N,N-dimethyl-formamide)</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1696917', constants.ctx, '0')">[3.3.1]nonane</a> <br />T=0 - 5&deg;C;&nbsp;1.33333&nbsp;h;&nbsp;<br />Stage #2: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587158', constants.ctx, '0')">hydrogen bromide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '506007', constants.ctx, '0')">acetic acid</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />&nbsp;Heating / reflux;&nbsp;<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 36 percent / Na, MeOH / CuI₂ / various solvent(s) / 16 h / Heating<br />2: 78 percent / 48percent HBr / 2 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 99 percent / I₂ / CHCl₃ / 18 h / Ambient temperature<br />2: 36 percent / Na, MeOH / CuI₂ / various solvent(s) / 16 h / Heating<br />3: 78 percent / 48percent HBr / 2 h / Heating<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587158', constants.ctx, '0')">hydrogen bromide</a> <br />2&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;<br /> &nbsp;