2,6-二甲基-4-氰基吡啶合成路线

113708-04-62,6-二甲基吡啶-4-羧酰胺→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Bolli, Martin; Lescop, Gyrille; Mathys, Boris; Mueller, Claus; Nayler, Oliver; Steiner, Beat
Patent: US2011/46170 A1, 2011 ;
Location in patent: Page/Page column 20 ;

151-50-8氰化钾+112950-66-0→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

CYCLACEL LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED
Patent: WO2008/122767 A2, 2008 ;
Location in patent: Page/Page column 60-61 ;

1073-23-02,6-二甲基吡啶 N-氧化物+151-50-8氰化钾→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

DOV PHARMACEUTICAL, INC.
Patent: WO2005/84439 A1, 2005 ;
Location in patent: Page/Page column 31 ;
WO 2005/084439 A1

151-50-8氰化钾→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Ochiai; Suzuki
Pharmaceutical Bulletin, 1954 , vol. 2, p. 247

99-11-6柠嗪酸→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Bolli, Martin; Lescop, Gyrille; Mathys, Boris; Mueller, Claus; Nayler, Oliver; Steiner, Beat
Patent: US2011/46170 A1, 2011 ;

99055-12-6→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Bolli, Martin; Lescop, Gyrille; Mathys, Boris; Mueller, Claus; Nayler, Oliver; Steiner, Beat
Patent: US2011/46170 A1, 2011 ;

557-21-1氰化锌+325142-95-82,6-二甲基吡啶-4-硼酸频那醇酯→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Liskey, Carl W.; Liao, Xuebin; Hartwig, John F.
Journal of the American Chemical Society, 2010 , vol. 132, # 33 p. 11389 - 11391

151-50-8氰化钾+87117-15-5→108-48-52,6-二甲基吡啶+39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Charier, Sandrine; Ruel, Odile; Baudin, Jean-Bernard; Alcor, Damien; Allemand, Jean-Francois; Meglio, Adrien; Jullien, Ludovic; Valeur, Bernard
Chemistry - A European Journal, 2006 , vol. 12, # 4 p. 1097 - 1113

1186513-01-8→39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Bolli, Martin; Lescop, Gyrille; Mathys, Boris; Mueller, Claus; Nayler, Oliver; Steiner, Beat
Patent: US2011/46170 A1, 2011 ;

1073-23-02,6-二甲基吡啶 N-氧化物→39965-81-62,6-二甲基-4-氰基吡啶+14993-80-7

参考文献

Okamoto; Tani
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 925,928
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Okamoto; Tani
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 130,925, 929