N6-苯甲酰基-2',3'-O-异丙亚基腺苷合成路线 （共 4 条）
反应条件
1: 58 percent / N,N-dimethyl-acetamide / 18 h / 37 °C 2: 1.) 30percent H2O2, CH3COOH, 2.) CH3ONa / 1.) r.t., overnight, 2.) methanol, reflux, 24 h 3: 90 percent / 10percent CH3COOOH / 1.5 h / Heating View Scheme
参考文献
Maki, Yoshifumi; Kameyama, Keiji; Suzuki, Mikio; Sako, Magoichi; Hirota, Kosaku
Journal of Chemical Research, Miniprint, 1984 , # 12 p. 3601 - 3654
反应条件
1: 93 percent / pyridine / 2 h / 0 °C 2: 80 percent / NaN3 / dimethylformamide / 1 h / 80 °C 3: 90 percent / hydrogen / 10 percent Pd/C / ethanol / 5 h / 20 °C View Scheme
参考文献
Ciuffreda, Pierangela; Loseto, Angela; Santaniello, Enzo
Tetrahedron, 2002 , vol. 58, # 29 p. 5767 - 5771
反应条件
1: 93 percent / pyridine / 2 h / 0 °C 2: 80 percent / NaN3 / dimethylformamide / 1 h / 80 °C View Scheme
参考文献
Ciuffreda, Pierangela; Loseto, Angela; Santaniello, Enzo
Tetrahedron, 2002 , vol. 58, # 29 p. 5767 - 5771
反应条件
1: 80 percent / TEMPO; bis(acetoxy)iodobenzene / acetonitrile; H2O
2: 100 percent / SOCl2 / CH2Cl2
3: 80 percent / CH2Cl2
4: 47 percent / H2O; PhCO2Ag / dioxane / Heating
5: 96 percent / MeONa / methanol
View Scheme
参考文献
Guillerm, Georges; Muzard, Murielle; Glapski, Cedric
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 23 p. 5799 - 5802
