反应条件
1.1: 84 percent / toluene / 2 h / Heating 2.1: tert-butyllithium / tetrahydrofuran; pentane / 3 h / -50 °C 2.2: 71 percent / tetrahydrofuran; pentane / -50 - 25 °C 3.1: tert-butyllithium / tetrahydrofuran; pentane / 0.25 h / -25 °C 3.2: 66 percent / tetrahydrofuran; pentane 4.1: 46 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 5 h / 80 °C View Scheme
参考文献
Zhang, Fan; Zhao, Yanfang; Sun, Li; Ding, Lu; Gu, Yucheng; Gong, Ping
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3149 - 3157