3-(4-氯苯甲酰)丙酸合成路线 （共 38 条）
反应条件
4,4'-diphenylsulfide; hydrogen; palladium on activated charcoal in methanol T=20°C; P=760 Torr; 24 h;
参考文献
Mori, Akinori; Mizusaki, Tomoteru; Miyakawa, Yumi; Ohashi, Eri; Haga, Tomoko; Maegawa, Tomohiro; Monguchi, Yasunari; Sajiki, Hironao
Tetrahedron, 2006 , vol. 62, # 51 p. 11925 - 11932
反应条件
aluminium trichloride T=20°C; Friedel-Crafts acylation; 0.416667 h;
参考文献
Mogilaiah; Reddy, N. Vasudeva; Reddy, G. Randheer
Synthetic Communications, 2003 , vol. 33, # 18 p. 3109 - 3113
反应条件
1: α-(4-Chlorophenyl)-4-morpholineacetonitrile With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.5 h; 2: acrylic acid methyl ester in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Pawar; Waghmare; Lokhande
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 11 p. 2549 - 2551
参考文献
Knott
Journal of the Chemical Society, 1947 , p. 1196,1200
参考文献
Dauben; Tilles
Journal of Organic Chemistry, 1950 , vol. 15, p. 785,787
反应条件
hydrogenchloride 1.) THF, 66 deg C, 2 h, 2.) THF; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Rahman, M. T.; Nur, H. P.
Journal of the Indian Chemical Society, 1994 , vol. 71, # 6-8 p. 469 - 474
反应条件
hydrazine hydrate in ethanol 17 h; Heating;
参考文献
Kane; Huber; Miller; Kehne
Pharmazie, 1992 , vol. 47, # 4 p. 249 - 251
反应条件
1: sodium acetate; hydrazine hydrate / methanol / 6 h / Reflux 2: trichlorophosphate / 6 h / Heating View Scheme
参考文献
Islam, Mojahidul; Siddiqui, Anees A.
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 555 - 562
反应条件
1: potassium borate 2: (i) SOCl2, (ii) HCl, /BRN= 1718733/ 3: NaOCMe2Et / benzene 4: KOH / methanol View Scheme
参考文献
Julia,M. et al.
Bulletin de la Societe Chimique de France, 1960 , p. 304 - 312
反应条件
potassium hydroxide; hydrazine hydrate in dichloromethane; water; diethylene glycol
参考文献
Larsen, Scott D.; May, Paul D.; Bleasdale, John E.; Liljebris, Charlotta; Schostarez, Heinrich Josef; Barf, Tjeerd; Nilsson, Marianne
Patent: US6410585 B1, 2002 ;
US 6410585 B1
