2-氯-5,6-二甲基-1H-苯并咪唑合成路线 （共 4 条）
反应条件
copper dichloride; sodium nitrite in water T=20 - 100°C; 2 h;
参考文献
NOVASAID AB; WANNBERG, Johan; ALTERMAN, Mathias; MALM, Johan
Patent: WO2012/117062 A1, 2012 ;
Location in patent: Page/Page column 38; 39 ;
反应条件
hydrogenchloride; trichlorophosphate T=150°C; 3 h;
参考文献
Orjales, Aurelio; Mosquera, Ramon; Labeaga, Luis; Rodes, Rosa
Journal of Medicinal Chemistry, 1997 , vol. 40, # 4 p. 586 - 593
反应条件
1: tetrahydrofuran / 4 h / Heating 2: POCl3; DBU / Heating View Scheme
参考文献
Orjales, Aurelio; Mosquera, Ramon; Labeaga, Luis; Rodes, Rosa
Journal of Medicinal Chemistry, 1997 , vol. 40, # 4 p. 586 - 593
参考文献
Alcalde, Ermitas; Dinares, Immaculada; Elguero, Jose; Fayet, Jean-Pierre; Vertut, Marie-Claire; et al.
Journal of Organic Chemistry, 1987 , vol. 52, # 22 p. 5009 - 5015
