4-(4-甲基苯基)-2,4-二氧代丁酸甲酯合成路线 (共 5 条)
反应条件
1: para-methylacetophenone With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 0.5 h; Inert atmosphere; 2: oxalic acid dimethyl ester in tetrahydrofuran; mineral oil T=45°C; 16 h; Inert atmosphereSonication;
参考文献
Lill, Andreas; Scholich, Klaus; Stark, Holger
Tetrahedron Letters, 2013 , vol. 54, # 49 p. 6682 - 6686
参考文献
Mumm; Hornhardt
Chemische Berichte, 1937 , vol. 70, p. 1930,1946
反应条件
1: hydroxylamine hydrochloride / methanol / 3 h / |Reflux 2: sodium hydroxide / tetrahydrofuran / 1 h / 60 °C View Scheme
参考文献
Kamal, Ahmed; Tamboli, Jaki R.; Vishnuvardhan; Adil; Nayak, V. Lakshma; Ramakrishna
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 273 - 280
反应条件
hydrazine hydrate; acetic acid 1 h; Reflux;
参考文献
Kamal, Ahmed; Tamboli, Jaki R.; Vishnuvardhan; Adil; Nayak, V. Lakshma; Ramakrishna
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 273 - 280
反应条件
Britton-Roninson buffer in water; isopropyl alcohol
pH=1.77; Electrochemical reaction;
参考文献
Posyagin; Posyagina; Zalesov; Kataev
Russian Journal of General Chemistry, 2001 , vol. 71, # 10 p. 1574 - 1577