2-羟基-3-硝基-6-甲基吡啶合成路线 （共 15 条）
反应条件
sulfuric acid; water; sodium nitrite T=0°C; 16 h;
参考文献
Beijing Yiling Bioengineering Co., Ltd.
Patent: EP2366691 A1, 2011 ;
Location in patent: Page/Page column 11 ;
反应条件
hydrogenchloride; sodium nitrite Diazotization;
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
反应条件
piperidinium acetate T=20°C; 48 h;
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
反应条件
1: concentrated H2SO4; concentrated HNO3 2: sodium nitrite; aqueous hydrochloric acid / Diazotization View Scheme
参考文献
Beijing Yiling Bioengineering Co., Ltd.
Patent: EP2366691 A1, 2011 ;
反应条件
1: liquid NH3; xylene; Fe(NO3)3 2: concentrated H2SO4; concentrated HNO3 3: sodium nitrite; aqueous hydrochloric acid / Diazotization View Scheme
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
反应条件
formic acid; sodium iodide
参考文献
Baumgarten et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 596,598
反应条件
hydrogenchloride; sodium nitrite 3 h; Ambient temperature;
参考文献
Troschutz; Karger
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1815 - 1821
反应条件
water; nitric acid; acetic acid
参考文献
Salemink; van der Want
Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 1013,1024
反应条件
bromine; phosphorus tribromide
参考文献
Brown; Burke
Journal of the American Chemical Society, 1955 , vol. 77, p. 6053
反应条件
trichlorophosphate 4 h; Reflux;
参考文献
Beijing Yiling Bioengineering Co., Ltd.
Patent: EP2366691 A1, 2011 ;
Location in patent: Page/Page column 11-12 ;
