N-(2-苯乙基)-4-哌啶酮合成路线 （共 32 条）
反应条件
1: With sodium t-butanolate in xylene T=20°C; Dieckmann reaction; 24 h; 2: With hydrogenchloride in water 2 h; Heating; Further stages.;
参考文献
Fakhraian; Panbeh Riseh, M. Babaei
Organic Preparations and Procedures International, 2008 , vol. 40, # 3 p. 307 - 310
反应条件
caesium carbonate in acetonitrile 6 h; Reflux;
参考文献
AUSPEX PHARMACEUTICALS, INC.
Patent: US2010/16365 A1, 2010 ;
Location in patent: Page/Page column 19 ;
US 20100016365 A1
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78°C;
参考文献
Suh, Young-Ger; Shin, Dong-Yun; Cho, Kyung-Ho; Ryu, Jae-Sang
Heterocycles, 1998 , vol. 48, # 2 p. 239 - 242
反应条件
hydrogenchloride in benzene 24 h; Heating;
参考文献
Dutta; Xu; Reith
Journal of Medicinal Chemistry, 1996 , vol. 39, # 3 p. 749 - 756
反应条件
hydrogenchloride Heating;
参考文献
Janssens; Torremans; Janssen; Stokbroekx; Luyckx
Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1925 - 1933
反应条件
hydrogenchloride in water
参考文献
Sun, Chuan-Wen; Wang, Hai-Feng; Zhu, Jun; Yang, Ding-Rong; Xing, Jiahua; Jin, Jia
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 6 p. 1374 - 1380
反应条件
sodium; xylene Erwaermen des Reaktionsprodukts mit wss. Salzsaeure;
参考文献
Elpern et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 4916
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Beckett et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1959 , vol. 1, p. 37,54
反应条件
1: 73 percent / potassium carbonate / dimethylformamide / 70 °C 2: 81 percent / aq.HCl / benzene / 24 h / Heating View Scheme
参考文献
Dutta; Xu; Reith
Journal of Medicinal Chemistry, 1996 , vol. 39, # 3 p. 749 - 756
反应条件
1: 73 percent / potassium carbonate / dimethylformamide / 70 °C 2: 81 percent / aq.HCl / benzene / 24 h / Heating View Scheme
参考文献
Dutta; Xu; Reith
Journal of Medicinal Chemistry, 1996 , vol. 39, # 3 p. 749 - 756
反应条件
1: With triethylamine in dichloromethane T=20°C; 0.5 h; 2: With sodium tris(acetoxy)borohydride in dichloromethane T=20°C; 24 h;
参考文献
Gupta, Pradeep Kumar; Ganesan, Kumaran; Pande, Ambuja; Malhotra, Ramesh Chandra
Journal of Chemical Research, 2005 , # 7 p. 452 - 453
