2-[(4-氯苯甲酰基)氨基]乙酸乙酯合成路线 （共 14 条）
反应条件
tert.-butylhydroperoxide; calcium carbonate in water T=60°C; 16 h; Inert atmosphereGreen chemistry;
参考文献
Ghosh, Subhash Chandra; Ngiam, Joyce S.Y.; Seayad, Abdul M.; Tuan, Dang Thanh; Johannes, Charles W.; Chen, Anqi
Tetrahedron Letters, 2013 , vol. 54, # 36 p. 4922 - 4925
反应条件
copper(l) iodide; calcium carbonate in water; acetonitrile T=40°C; 6 h;
参考文献
Yoo, Woo-Jin; Li, Chao-Jun
Journal of the American Chemical Society, 2006 , vol. 128, # 40 p. 13064 - 13065
反应条件
in tetrahydrofuran T=0 - 20°C; 3 h;
参考文献
Pessoa-Mahana, Hernan; Astudillo, Claudio I. O.; Araya-Maturana
Synthetic Communications, 2002 , vol. 32, # 9 p. 1437 - 1445
反应条件
1: SOCl2, DMF / toluene / 0.5 h / 60 - 70 °C 2: K2CO3 / H2O; toluene / -5 - 5 °C View Scheme
参考文献
Munakata; Tanaka; Toyoshima
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051
反应条件
1: 38 percent / lead tetra-acetate / CH2Cl2; acetic acid / 0.5 h / 0 °C 2: triethylamine / dioxane / 0.17 h / Ambient temperature View Scheme
参考文献
Theocharis, A.B.; Maroulis, A.J.; Hadjiantoniou-Maroulis, C.P.; Alexandrou, N.E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 619 - 621
反应条件
1: methanol / Ambient temperature 2: 38 percent / lead tetra-acetate / CH2Cl2; acetic acid / 0.5 h / 0 °C 3: triethylamine / dioxane / 0.17 h / Ambient temperature View Scheme
参考文献
Theocharis, A.B.; Maroulis, A.J.; Hadjiantoniou-Maroulis, C.P.; Alexandrou, N.E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 619 - 621
反应条件
1: Iron (III) nitrate nonahydrate; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical / acetonitrile / 2 h / 20 °C / |Inert atmosphere; |Green chemistry 2: tert.-butylhydroperoxide; calcium carbonate / water / 16 h / 60 °C / |Inert atmosphere; |Green chemistry View Scheme
参考文献
Ghosh, Subhash Chandra; Ngiam, Joyce S.Y.; Seayad, Abdul M.; Tuan, Dang Thanh; Johannes, Charles W.; Chen, Anqi
Tetrahedron Letters, 2013 , vol. 54, # 36 p. 4922 - 4925
反应条件
triethylamine in 1,4-dioxane 0.166667 h; Ambient temperature; Yield given;
参考文献
Theocharis, A.B.; Maroulis, A.J.; Hadjiantoniou-Maroulis, C.P.; Alexandrou, N.E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 619 - 621
反应条件
1,1'-carbonyldiimidazole 1) DMF, 0 deg C -> room temperature, 20 min, 2) DMF, room temperature, 30 min; Yield given. Multistep reaction;
参考文献
Conway, Samuel C.; Perni, Robert B.
Synthetic Communications, 1998 , vol. 28, # 9 p. 1539 - 1545
反应条件
in 1,4-dioxane; water effect of water on the yield; Rate constantProduct distribution;
参考文献
Imrich, Jan; Kristian, Pavol; Podhradsky, Dusan; Dzurilla, Milan
Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 8 p. 2334 - 2342
