1: With sulfuric acid T=20°C; 48 h; 2: With acetic acid in water 2 h; Further stages.;

sodium carbonate; sulfuric acid in acetone

acetic acid T=40°C; 2 h;

methanol; sodium methylate T=20°C; 5 h;

H-Beta zeolite; water in methanol T=20°C; 6 h; Product distribution; Further Variations:Reagentsreaction time; molar ratio;

暂无反应条件数据

暂无反应条件数据

1: 1.) sodium periodate, 2.) NaBH4 / 1.) aq. acetone, 0 deg C, 2 h, 2.) O deg C, 1 h 2: 81 percent / pyridine / 2 h / 0 °C View Scheme

1.1: sodium periodate; sodium hydrogencarbonate / water / 3 h / 0 - 8 °C 1.2: 17 h / 20 °C 2.1: hydrogen / palladium 10 on activated carbon / methanol / 3102.97 Torr 3.1: trifluoroacetic acid / acetonitrile; water / 6 h / Reflux 4.1: lithium hexamethyldisilazane; N2,N2-dimethyl-2-methyl-1,2-propanediamine / tetrahydrofuran / 3 h / -78 °C 4.2: 3 h / -78 °C 5.1: pyridine; trichlorophosphate / 12.5 h / 10 - 20 °C 5.2: 0 °C / pH 5.5 6.1: hydrogen / palladium 10 on activated carbon / methanol / 3102.97 Torr 7.1: n-butyllithium; N2,N2-dimethyl-2-methyl-1,2-propanediamine / tetrahydrofuran; tetrahydro-4H-pyran / 1.33 h / -78 °C 7.2: 1.33 h / -78 °C 7.3: -78 °C / pH 7 8.1: triethylamine / dichloromethane / -10 °C 9.1: tetra(n-butyl)ammonium hydrogensulfate; sodium azide / N,N-dimethyl-formamide / 36 h / 90 °C 10.1: triethylamine; hydrogen / palladium 10 on activated carbon / ethanol; water / 16 h / 3102.97 Torr 11.1: potassium hydroxide / water; tetrahydrofuran; methanol / 10 h / 0 °C 11.2: 10 h / 0 - 20 °C 12.1: triethylamine; 2-hydroxy-pyridine / 48 h / 90 °C 13.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C View Scheme

lead(IV) acetate; nickel; ethyl acetate Hydrogenation;